Avaliação do eixo hipotálamo-hipófise-adrenal em indivíduos com e sem mediunidade (experiência anômala) em um contexto religioso
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Data
2017-10-30
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Universidade Federal de Goiás
Resumo
Objective - To evaluate the HPA axis and the mental health status in a non-pathological
dissociation condition (mediumship)
Methods - In this prospective and controlled study, 29 psychophonic mediums (group 1) were
evaluated before and after psychophony and compared to 22 non-medium volunteers of the same
religious context (group 2) before and after a creative visualization, simulating a mediumistic
assistance. Plasma catecholamines, ACTH, cortisol and glucose were measured pre-and 1 hour
after the intervention. A structured questionnaire - DDIS was applied (Dissociative Disorders
Interview Schedule) and the results were compared with historical data from patients with
dissociative disorder (DD) who answered the DDIS.
Results - In group 1, cortisol and ACTH decreased (14.7 μg/dl to 11.2 μg/dl with p-0.001 and
20.6 pg/ml to 13.9 pg/ml with p-0.001, respectively), However, the HPA axis showed diversified
responses with epinephrine and noradrenaline decreasing after the intervention (39 pg/ml at 33
pg/ml and 311.2 pg/ml at 284.1 pg/ml, respectively) and an increased in dopamine (41.7 pg/ml to
44.4 pg/ml with p-0.046). In group 2, cortisol decreased from 15.5 μg/dl to 13.4 μg/dl (p -0.01).
The scores obtained in the structured interview (DDIS) were similar in both groups, but with
considerable differences when compared with historical data from TD patients.
Conclusion - This study showed that one hour after psychophony the HPA axis remains
preserved in mediums. Dopamine is the main neurochemistry of religious manifestations and may
eventually constitute a biomarker of this phenomenon.
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Palavras-chave
Dopamina , Mediunidade , Dissociação , DDIS , Transe mediúnico , Dopamine , Dissociation , Mediumship , Trance
Citação
VENCIO, S. Avaliação do eixo hipotálamo-hipófise-adrenal em indivíduos com e sem mediunidade (experiência anômala) em um contexto religioso. 2017. 137 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2017.