Perfil de pacientes intoxicados investigados no estado de Goiás entre os anos 2007 a 2012
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2017-06-30
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Universidade Federal de Goiás
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Introduction: Substance, of easy access to the population, as cleaners’ substances, cosmetics,
medicines and chemical’s industries products are examples for sources of intoxications.
Toxicological Information Centers (CITs) informs about intoxications and register the cases in
information systems (SINAVISA). The evaluation of a big data need care, because to be
accomplished its necessary the use of statistics methods to monitor constantly of a big data.
Objective: To perform quality control of data in variables product and “chemistry group”, and to
evaluate the profile of intoxications of patients notified in SINAVISA, during the period of 2007 to
2012. Methodology: In the first moment it was evaluated the cadasters in variables product and
“chemistry group” with Textual Analysis. Posteriorly was evaluated variables of 5041
investigations files of intoxications by medicines and 16333 investigations files of intoxication by
medicines, cosmetics, toxic plants, cleaners’ substance, chemical’s industries products,
rodenticides, foods, abuse drugs, vets products and agrotoxics, except files from intoxication by
venomous’ animals, with Multiple Correspondence Analysis (MCA) and Hierarchical Cluster
Analysis (HCA). Results: It was observed the presence of discordances on data of product and
“chemistry group” and then corrected. In analysis of medicine observed that, children and women
are the principal victims of intoxication by medicines. The “chemical groups” that more affected
on children with 1 to 4 years old was antibiotics, anti-inflammatories not steroidal, antipsychotics,
adrenergics agonists, hormones and anti-histaminics. The children with less than one-year-old
presented intoxication with ignored products, antibacterial, sympathomimetics agonists,
antagonists and anti-inflammatories. Patients with age of 20 to 29 years, female gender, intoxicated
by anxiolytics, antidepressives and anticonvulsants. Analysis of 16333 investigations files observed
that severe intoxications are in chemical’s group agrotoxics, as pyrethroids, organophosphates,
glycine, coumarins and carbamates. The ignored products were grouped in clusters with tendency
to more severity. Children with age less than 4 years old also intoxicated with acids, rodenticides,
and agrotoxics, but with less frequency. Conclusion: The method was capable of corrected the
errors presents in variables “chemical group” and product. Additionally, it was traced the following profile: children intoxicated with medicines antibiotics, anti-inflammatories not steroids,
antipsychotics, adrenergics agonists, hormones and anti-histaminics, and young adults intoxicated
with agrotoxics, rodenticides and medicines anxiolytics, anti-depressives and anticonvulsants.
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OLIVEIRA, Flávia Neri Meira de. Perfil de pacientes intoxicados investigados no estado de Goiás entre os anos 2007 a 2012. 2017. 212 f. Tese (Doutorado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2017.