Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma

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2018-11-19

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Universidade Federal de Goiás

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The aim of this study was to assess and compare the influence of Visual Field (VF) and/or Optical Coherence Tomography (OCT) when analyzed in association with Color Retinography (CR) to differentiate glaucomatous patients from those with increased physiological cupping, by non-glaucoma specialists. Eighty patients were selected, half with glaucoma and half with physiological cupping. The patients were randomized into 4 groups according to the exam performed on their right eye, which would be shown through Power Point slides to 20 non-specialist ophthalmologists: GI (CR), GII (CR + VF), GIII (CR + OCT), GIV (CR + VF + OCT). The ophthalmologists completed a questionnaire in which they checked whether or not the patient was glaucomatous, without direct examination of the patient. Inter-rater agreement determined by Kappa test was good for GII (k: 0.63; 95% CI,0.53-0.72), moderate for GIII (k:0.58; 95% CI,0.48-0.68) and for GIV (k: 0.41; 95% CI,0.31-0.51) and low for GI (k:0.30; 95% CI,0.20-0.39), the difference among groups being statistically significant (p<0.001). Statistically significant difference was found regarding correct diagnoses among groups, GIII being higher (15.8 ± 1.82) in comparison with GI (12.95 ± 1.46), (p<0.001); and higher for GII (16.25 ± 2.02) when compared to GI and GIV (14.10 ± 2.24), for both p<0.001. We found higher values for GII and GIII (p<0.001) regarding correct diagnoses of slides with glaucomatous patients single-handedly. Sensitivity and Specificity for each group were respectively: GI (59% and 70.5%); GII (86.5% and 76%); GIII (86.5% and 71.5%); GIV (68.5% and 72.5%). Accuracy was higher for GII 81.3% (95% CI,77.1-84.8), followed by GIII 79% (95% CI,74.7-82.7), GIV 70,5% (95% CI,65.9-74.8) and lower for GI 64.8% (95% CI, 60.0-69.3). We concluded that isolated assessment of CR by non-glaucoma specialists failed to properly differentiate glaucomatous patients from those with increased physiological cupping. We detected a significant increase in diagnostic accuracy and inter-rater agreement when either VF or OCT is employed. Increase for Sensitivity and Specificity was not detected for both.

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FRANCO, Cláudia Gomide Vilela de Sousa. Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma. 2018. 65 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2018.