Suplementação e metabolismo de biotina em bovinos
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Data
2015-12
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Resumo
Biotin is a B-group vitamin that is involved in many metabolic pathways, among them:
lipogenesis, gluconeogenesis, synthesis and degradation of fatty acids and leucine
degradation. Biotin acts as a cofactor of four carboxylases: Acetyl-CoA carboxylase
(ACC), propionyl-CoA carboxylase (PCC), pyruvate carboxylase (PC) and β-methylcrotonyl-CoA carboxylase (MCC). It’s main function is the transport of carbon
dioxide (CO2) in carboxylation, decarboxylation and transcarboxylation reactions.
Biotin also acts as an important cofactor in the development of cornified tissues and it
is involved in epidermal cell differentiation processes, keratinization and intercellular
cementing substance (ICS) production. In ruminants, biotin deficiency is rare,
because the rumen microflora is able to synthesize this vitamin in sufficient quantities
to the animal supplement needs. However, studies have shown that cattle biotin
supplementation promotes positive effects on hoof health and milk production. It is
believed that the improvement of biotin for hoof quality is caused by the increased
production of lipids that compose the ICS and increased production of keratin.
However, the mechanisms involved in these processes have not been fully clarified.
Therefore, biotin supplementation for cattle is a nutritional management that should
be considered by producers and veterinarians to reduce spending on digital disease
treatments and increase milk production.
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Palavras-chave
Carboxilação, Casco, Gliconeogênese, Queratina, Produção leiteira, Carboxylation, Gluconeogenesis, Hoof, Keratin, Milk production
Citação
QUEIROZ, Paulo José Bastos; ÁVILA FILHO, Saulo Humberto de; FERREIRA, Kamilla Dias; SANTOS, Thais Poltronieri dos; SILVA, Luiz Antônio Franco da. Suplementação e metabolismo de biotina em bovinos. Enciclopédia Biosfera, Goiânia, v. 11, n. 22, p. 2589-2618, dez. 2015.