Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/14381
Tipo do documento: Artigo
Título: Cytotoxicity tests for nanostructured Chitosan/PEO membranes using the agar diffusion method
Autor: Vulcani, Valcinir Aloisio Scalla
Bizarria, Maria Trindade Marques
D’Ávila, Marcos Akira
Mei, Lucia Helena Innocentini
Bernal, Cláudia
Perussi, Janice Rodrigues
Resumo: Electrospinning is used to produce fibers in the nanometer range by stretching a polymeric jet using electric fields of high magnitude. Chitosan is an abundant natural polymer that can be used to obtain biocompatible nanostructured membranes. The objectives of this work were to obtain nanostructured membranes based on blends of chitosan and polyoxyethylene (PEO), and evaluate their thermal and morphological properties, as well as their in vitro biocompatibility by agar diffusion cytotoxicity tests for three different cell lines. A nanostructured fibrous membrane with fiber diameters in the order of 200 nm was obtained, which presented a rough surface and thickness ranging from one to two millimeters. The results of the cytotoxicity tests evidenced that the chitosan/PEO membranes are non-toxic to the cells studied in this work. Further, the electrospinning technique was effective in obtaining nanostructured chitosan/PEO membranes, which showed biocompatibility according to in vitro preliminary tests using the cell lines.
Palavras-chave: Nanotechnology
Biomaterials
Biocompatibility
Electrospinning
País: Brasil
Unidade acadêmica: Escola de Veterinária e Zootecnia - EVZ (RG)
Citação: VULCANI, Valcinir Aloisio Scalla; BIZARRIA, Maria Trindade Marques; D’ÁVILA, Marcos Akira; MEI, Lucia Helena Innocentini; BERNAL, Cláudia; PERUSSI, Janice Rodrigues. Cytotoxicity tests for nanostructured chitosan/PEO membranes using the agar diffusion method. Materials Research, São Carlos, v. 15, n. 2, p. 213-217, 2012.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S1516-14392012005000013
Identificador do documento: 10.1590/S1516-14392012005000013
URI: http://repositorio.bc.ufg.br/handle/ri/14381
Data de publicação: 2012
Aparece nas coleções:EVZ - Artigos publicados em periódicos

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