Intoxicação aguda por triclorfon em caprinos tratados com a dose terapêutica
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Data
2014-02
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Resumo
The present study describes an outbreak of trichlorfon poisoning in goats from the State
University of Maringá, campus Umuarama/PR that received orally the therapeutic dose
of the active ingredient in question (100mg/kg). Fifty-three sheep had been treated with
the same formulation/solution and no side effects were observed in any of these sheep medicated
with triclorfon. But from 20 goats medicated with trichlorfon, eight goats showed,
about 40 minutes after its administration, the classic clinical signs of ataxia, external lateral
decubitus, drooling, tremors, constricted pupils, noisy dyspnea, involuntary urination and
defecation, spastic paresis, bloat and tearing. Almost immediately after the detection of
these signals, eight goats were medicated with 1% atropine sulfate (0.5mg/kg and fluid).
Five of these goats received a second dose of atropine sulfate one hour after the first application
because of some clinical signs such as muscle tremor still being present. Forty-eight
to 72 hours after administration of trichlorfon, three of those five goats died. At necropsy
we observed cyanotic mucous membranes, congestion of liver, spleen, kidneys and mesenteric
vessels, filled gallbladder, emphysema, and reddish lungs. The results of this study call
attention to the outbreak that occurred in adult goats in good clinical conditions and, above
all, that they received the therapeutic dosage recommended on the manufacture label.
This suggests a higher sensitivity of the species to the recommended dose of trichlorfon
(100mg/kg) for goats.
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Intoxicação, Inseticida, Organofosforados, Triclorfon, Caprinos, Poisoning, Insecticide, Organophosphate, Triclorfon, Goats
Citação
LOPES, Welber Daniel Zanetti; CARVALHO, Rafael Silveira; GRACIOLI, Diogo dos Passos; OLIVEIRA, Pedro Victor; PEREIRA, Valdomiro; MARTINEZ, Antônio Campanha; MAZZUCATTO, Barbara Cristina. Intoxicação aguda por triclorfon em caprinos tratados com a dose terapêutica. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 34, n. 2, p. 114-118, fev. 2014.