Uma visão da química bioinorgânica medicinal

Resumo

Metals play a vital role in human and plant physiology and important research is directed towards exploring the interrelated mechanisms that govern their interactions with biomolecules. Bioinorganic medicinal chemistry studies the functions, processing, storage and applications of metal ions and their complexes in biological systems. This paper presents a brief discussion about on interactions of metals with biomolecules that determine their intracellular accumulation, where metal ions may fulfill essential functions in cellular metabolism or, in certain cases, exert toxic effects towards cells.

Descrição

Palavras-chave

Metals, Coordination chemistry

Citação

BENITE, Anna Maria Canavarro; MACHADO, Sérgio de Paula; BARREIRO, Eliezer J. Uma visão da química bioinorgânica medicinal. Química Nova, São Paulo, v. 30, n. 8, p. 2062-2067, 2007.