Importancia de los compuestos inorgánicos en el tratamiento de la Leishmaniasis
Carregando...
Data
2007
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
La leishmaniasis, infección por protozoarios tripanosomátidos del género Leishmania sp, es
una enfermedad endémica que abarca mas de 80 países incluyendo algunos del continente europeo y principalmente
los países en vías de desarrollo. En esta revisión son mostradas las opciones terapéuticas usuales
enfocando principalmente sus mecanismos de acción y de resistencia, farmacocinética y toxicidad. Asimismo,
son presentados los intentos de aplicación de agentes quimioterápicos, en especial los compuestos
organometálicos derivados de ligandos potencialmente activos.
The Importance of Inorganic Compounds in Leishmaniasis Treatment”. Leishmaniasis is a parasitic disease caused by protozoan genus Leishmania. It is an endemic illness that encloses 80 countries, including some of the European continent and especially in development countries. In this revision the usual therapeutical options, focusing mechanisms of action and resistance, pharmacokinetics and toxicity are discussed . Additionally, the attempts for application of other chemotherapeutical drugs, especially organometalic substances derivatives of potencial active ligands, are also cited
The Importance of Inorganic Compounds in Leishmaniasis Treatment”. Leishmaniasis is a parasitic disease caused by protozoan genus Leishmania. It is an endemic illness that encloses 80 countries, including some of the European continent and especially in development countries. In this revision the usual therapeutical options, focusing mechanisms of action and resistance, pharmacokinetics and toxicity are discussed . Additionally, the attempts for application of other chemotherapeutical drugs, especially organometalic substances derivatives of potencial active ligands, are also cited
Descrição
Palavras-chave
Leishmaniasis, Leishmanicidas, Mecanismos de acción, Action mechanisms, Antileishmaniasis, Leishmaniasis
Citação
GIL, Eric de Souza et al. Importancia de los compuestos inorgánicos en el tratamiento de la Leishmaniasis. Acta Farmaceutica Bonaerense, Buenos Aires, v. 26, n. 3, p. 454-461, 2007.