Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae
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Data
2010-09
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Resumo
The antioxidant activity, evaluated by DPPH (1,1-difenil-2-picrilidrazila) method, and the
determination of the total phenolic compounds of the crude methanolic extract and fractions of the
Palicourea rigida Kunth, Rubiaceae, leaves were quantified in this work. Despite weak activity
exhibited by crude extract (500 ppm), the fraction ethyl acetate showed moderate activity (192
ppm), and the largest value for the phenolic compounds among all the assayed fractions. Then, the
ethyl acetate fraction was submitted to the chromatography procedures which led to the isolation of
the flavonoid quercetin 3-O-D-glicoside, quercetin 3-O-sophoroside and isorhamnetin 3-glicoside,
which had the structures elucidated by spectroscopy analysis, including RMN (1D and 2D) and
comparison with literature data.
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Rubiaceae, Palicourea, Flavonoides, Atividade antioxidante, Flavonoids, Antioxidant activity
Citação
ROSA, Elisa A. da et al. Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae. Revista Brasileira de Farmacognosia, Curitiba, v. 20, n. 4, p. 484-488, ago./set. 2010.