Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15419
Tipo do documento: Artigo
Título: Hepatitis B virus infection among institutionalized mentally ill patients in Brazil
Autor: Moraes, Tatiane Cinquini
Fiaccadori, Fabíola Souza
Souza, Menira Borges de Lima Dias e
Almeida, Tâmera Nunes Vieira
Cunha, Marielton dos Passos
Castro, Ítalo de Araújo
Cardoso, Divina das Dôres de Paula
Abstract: Objectives: The main objective was to evaluate HBV infection and occult HBV infection (OBI) cases in mentally ill patients based on serological and molecular profiles. Material and methods: Serum samples of 333 long-stay mentally ill patients were tested for the prevalence of HBV markers by serological (ELISA) and molecular (PCR) assays. The PCR products were sequenced to determine viral genotypes. Results: It was observed a global prevalence of 12.9% (43/333) for HBV infection markers, considering HBsAg and/or anti-HBc positivity. Fourteen samples tested positive for anti-HBs alone. All samples positive (n = 57) for any HBV serological markers were tested for HBV-DNA and six were positive: HBsAg/anti-HBc (n = 1), anti-HBc/anti-HBs (n = 1), anti-HBs alone (n = 1), and anti-HBc alone (n = 3). The rate of OBI was 9.2% (5/54) from samples that were anti-HBc and/or anti-HBs positive. All sequenced samples were characterized as genotype A. Conclusion: The high rate of HBV infections found in this study suggests the possibility of HBV transmission due to risk factors displayed by some patients, and highlights the importance of vaccination of susceptible patients and the staff of that institution.
Palavras-chave: Hepatitis B virus
Occult infection
Prevalence
Mental illness
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: MORAES, Tatiane Cinquini; FIACCADORI, Fabíola Souza; SOUZA, Menira; ALMEIDA, Tâmera Nunes Vieira; CUNHA, Marielton dos Passos; CASTRO, Ítalo de Araújo; CARDOSO, Divina das Dôres de Paula. Hepatitis B virus infection among institutionalized mentally ill patients in Brazil. Brazilian Journal of Infectious Diseases, Salvador, v. 19, n. 6, p. 643-647, Nov./Dec. 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1016/j.bjid.2015.07.007
Identificador do documento: 10.1016/j.bjid.2015.07.007
URI: http://repositorio.bc.ufg.br/handle/ri/15419
Data de publicação: Dez-2015
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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