Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16731
Tipo do documento: Artigo
Título: GB virus C/Hepatitis G virus infection in dialysis patients and kidney transplant recipients in central Brazil
Autor: Ramos Filho, Ramon
Carneiro, Megmar Aparecida dos Santos
Teles, Sheila Araújo
Matos, Márcia Alves Dias de
Cardoso, Divina das Dôres de Paula
Lampe, Elisabeth
Yoshida, Clara Fumiko Tachibana
Martins, Regina Maria Bringel
Abstract: In order to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection in dialysis patients and kidney transplant recipients in Central Brazil and also to analyze the virus genotypes distribution, a total of 123 patients including 98 on hemodialysis, 13 on continuous ambulatory peritoneal dialysis treatment, and 12 who received kidney transplantation were interviewed in one unit of dialysis treatment in Goiânia city. Blood samples were collected and serum samples tested for GBV-C/HGV RNA by polymerase chain reaction. Genotypes were determined by restriction fragment length polymorphism (RFLP) analysis. Eighteen samples were GBV-C/HGV RNA-positive, resulting in an overall prevalence of 14.6% (95% CI: 9.2-21.7). A high positivity for GBV-C/HGV RNA was observed in patients who had received kidney transplant (16.7%), followed by those on hemodialysis (15.3%), and peritoneal dialysis (7.7%). RFLP analysis revealed the presence of genotypes 1, 2, and 3 of GBV-C/HGV; more precisely, 9 (50%) samples were found belonging to the 2b subtype, 4 (22%) to the 2a subtype, 3 (17%) to genotype 1, and 2 (11%) to genotype 3. The present data indicate an intermediate prevalence of GBV-C/HGV infection among dialysis patients and kidney transplant recipients in Central Brazil. Genotype 2 (subtype 2b) seems to be the most prevalent GBV-C/HGV genotype in our region.
Palavras-chave: Central Brazil
Hepatitis G virus
GB virus C
Dialysis
Kidney transplant
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: RAMOS FILHO, Ramon et al. GB virus C/Hepatitis G virus infection in dialysis patients and kidney transplant recipients in central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 6, p. 639-643, 2004.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0074-02762004000600019
Identificador do documento: 10.1590/S0074-02762004000600019
URI: http://repositorio.bc.ufg.br/handle/ri/16731
Data de publicação: Out-2004
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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