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Tipo do documento: Artigo
Título: Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?
Autor: Moreira, Marina Conceição dos Santos
Pinto, Izabella Silva de Jesus
Mourão, Aline Andrade
Fajemiroye, James Oluwagbamigbe
Colombari, Eduardo
Reis, Angela Adamski da Silva
Oliveira, André Henrique Freiria de
Ferreira-Neto, Marcos Luiz
Pedrino, Gustavo Rodrigues
Abstract: The metabolic syndrome (MS), formally known as syndrome X, is a clustering of several risk factors such as obesity, hypertension, insulin resistance, and dislypidemia which could lead to the development of diabetes and cardiovascular diseases (CVD). The frequent changes in the definition and diagnostic criteria of MS are indications of the controversy and the challenges surrounding the understanding of this syndrome among researchers. Obesity and insulin resistance are leading risk factors of MS. Moreover, obesity and hypertension are closely associated to the increase and aggravation of oxidative stress. The recommended treatment of MS frequently involves change of lifestyles to prevent weight gain. MS is not only an important screening tool for the identification of individuals at high risk of CVD and diabetes but also an indicator of suitable treatment. As sympathetic disturbances and oxidative stress are often associated with obesity and hypertension, the present review summarizes the role of sympathetic nervous system and oxidative stress in the MS.
Palavras-chave: Obesity
Central nervous system
Insulin resistance
Cardiovascular diseases
País: Suica
Unidade acadêmica: Instituto de Ciências Biológicas - ICB (RG)
Citação: MOREIRA, Marina Conceição dos Santos et al. Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome? Frontiers in Physiology, Lausanne, v. 6, p. e234, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.3389/fphys.2015.00234
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Identificador do documento: 10.3389/fphys.2015.00234
Data de publicação: 2015
Aparece nas coleções:ICB - Artigos publicados em periódicos

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