O peixe-zebra (Danio rerio) encontra a bioética: os princípios éticos dos 10Rs na pesquisa
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Data
2022-02-21
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Universidade Federal de Goiás
Resumo
Zebrafish (Danio rerio) is a tropical fish species widely used in research, worldwide. The development of genetically modified
animals and the increasing number of zebrafish breeding facilities due to their emerging use in several research fields, opened room
for new ethical challenges for research carried out with this species. It is necessary to raise the scientific community’s awareness of
the ethical standards and laws in force, on animal research. Thus, the aim of the current study is to describe 10 Rs ethical principles
by using zebrafish as model system in research. The classical 3 Rs concerning animal welfare, namely replacement, reduction and
refinement; and the added 7 Rs related to scientific (registration, reporting, robustness, reproducibility and relevance) and conduct
principles (responsibility, and respect) in zebrafish research are herein presented and critically discussed. The use of these 10 Rs by
researchers, institutions and the Animal Ethics Committee is recommended to support regulations, decision-making about and the
promotion of zebrafish health and welfare in research.
Descrição
Palavras-chave
Saúde animal, Bem-estar animal, Comitês de ética animal, Peixe, Animais de laboratório, Animal health, Animal welfare, Animal ethics committees, Fish, Laboratory animals
Citação
CANEDO, Aryelle; SAIKI, Patrícia; SANTOS, Andressa Liberal; CARNEIRO, Karla da Silva; SOUZA, Andreza Martins de; QUALHATO, Gabriel; BRITO, Rafaella da Silva; MELLO-ANDRADE, Francyelli; ROCHA, Thiago Lopes. O peixe-zebra (Danio rerio) encontra a bioética: os princípios éticos dos 10Rs na pesquisa. Ciência Animal Brasileira, Goiânia, v. 23, n. 1, e70884, 2022. Disponível em: https://www.revistas.ufg.br/vet/article/view/70884.