Circulating profile of rotavirus a, g and p genotypes before and after vaccine introduction in the Brazilian mid-west 1986-2015

Resumo

The purpose of this study was to perform a comparative analysis of Rotavirus A (RVA) G and P genotypes circulating in the Brazilian Mid-West in the period 1986-2015. Seven studies conducted from 1986 to 2009 were included, as well as fecal samples obtained in the period 2014-2015. RVA was screened by ELISA and/or PAGE; genotyping by conventional RT-PCR and/or genomic sequencing. A temporal variation in the predominance of G genotypes mainly G1 and G2 with G9 and G12 emergence was observed. Even with vaccination, RVA continues to circulate in the population, requiring continuous virus monitoring.

Descrição

Palavras-chave

Rotavirus infections, Genotype, Vaccination

Citação

ALMEIDA, Tâmera Nunes Vieira; SOUSA, Teresinha Teixeira de; SOUZA, Menira; FIACCADORI, Fabíola Souza; BADR, Kareem Rady; CARDOSO, Divina das Dôres de Paula. Circulating profile of rotavirus a, g and p genotypes before and after vaccine introduction in the Brazilian mid-west 1986-2015. Revista de Patologia Tropical, Goiânia, v. 46, n. 1, p. 105-112, jan./mar. 2017. Disponível em: <https://www.revistas.ufg.br/iptsp/article/view/46300/22815>.