Detecção de metalo-beta-lactamase em Pseudomonas aeruginosa isoladas de pacientes hospitalizados em Goiânia, Estado de Goiás
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Data
2009-08
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Resumo
Pseudomonas aeruginosa is a bacterium frequently isolated from hospital environments. This study had the aims of evaluating the susceptibility profile of Pseudomonas aeruginosa previously isolated from patients in a hospital in Goiânia (Goiás, Brazil), performing phenotypic screening for metallo-beta-lactamase production and detecting its genes using the polymerase chain reaction technique. Seventy-five 75 Pseudomonas aeruginosa isolates were evaluated between January 2005 and January 2007. Biochemical identification was performed using the API 20E® system and an antibiogram was produced using the Kirby-Bauer method. Among the 62 isolates that were resistant to imipenem and ceftazidime, 35 (56.4%) produced metallo-beta-lactamase, while 26 (74.3%) showed the blaSPM-1 gene. The frequency of Pseudomonas aeruginosa that produces metallo-beta-lactamase suggests that greater control over the dissemination of resistance in hospital environments is needed.
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Pseudomonas aeruginosa, Metalo-beta-lactamase, Infecção nosocomial, Carbapenêmicos, Multirresistência, Pseudomonas aeruginosa, Metallo-beta-lactamase, Nosocomial infection, Carbapenems, Multiresistance
Citação
GONÇALVES, Diana Christina Pereira Santos; LIMA, Ana Beatriz Mori; LEÃO, Lara Stefania Netto de Oliveira; CARMO FILHO, José Rodrigues do; PIMENTA, Fabiana Cristina; VIEIRA, José Daniel Gonçalves. Detecção de metalo-beta-lactamase em Pseudomonas aeruginosa isoladas de pacientes hospitalizados em Goiânia, Estado de Goiás. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 42, n. 4, p. 411-414, jul./ago. 2009.