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dc.creatorCosta, Carolina Rodrigues-
dc.creatorMarreto, Lais Carneiro Nassiazene Lima-
dc.creatorRocha, Viviane Lopes-
dc.creatorSilva, Thaisa Cristina da-
dc.creatorSilva, Maria do Rosário Rodrigues-
dc.identifier.citationCOSTA, Carolina Rodrigues; MARRETO, Lais Carneiro Nassiazene Lima; ROCHA, Viviane Lopes; SILVA, Thaisa Cristina da; SILVA, Maria do Rosário Rodrigues. Biofilm forming capability and antifungal susceptibility profile of candida spp. from blood. Revista de Patologia Tropical, Goiânia, v. 47, n. 3, p. 159-166, jul./sep. 2018. Disponível em:
dc.identifier.issne- 1980-8178-
dc.description.abstractAlthough Candida albicans remains the most frequent Candida species; however other species have emerged as important causes of candidiasis. In this work, we evaluated the in vitro susceptibility profile of C. albicans, C. parapsilosis, and C. tropicalis biofilms isolated from patients with candidemia to fluconazole, voriconazole, amphotericin B, and caspofungin. Differences between the biofilm ultrastructure of the three species were also determined. The isolates were phenotypically determined by growth on a ChromagarTM medium and assimilation profile on ID32C. The Scanning Electron Microscopy method (SEM) on biofilm was performed using polyurethane strips. For the in vitro susceptibility profile a microdilution in broth was used. Sessile cells were resistant to fluconazole, voriconazole and caspofungin. The resistance to amphotericin B was less pronounced and more variable between the tested isolates. In the SEM, slight differences in ultrastructural morphology for each species in biofilms were observed. Our results verified biofilm formation. Low susceptibility to the drugs in the three researched species confirmed the higher virulence of them.pt_BR
dc.description.sponsorshipSociedade Brasileira de Parasitologiapt_BR
dc.publisherRuy de Souza Lino Juniorpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCandida spp.pt_BR
dc.subjectIn vitro susceptibilitypt_BR
dc.subjectScanning electron microscopypt_BR
dc.titleBiofilm forming capability and antifungal susceptibility profile of candida spp. from bloodpt_BR
dc.publisher.departmentInstituto de Patologia Tropical (IPTSP) - RGpt_BR
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