A comparative study of the organic content of the hemolymph of Schistosoma mansoni-resistant and susceptible strains of Biomphalaria glabrata

Página do item simplificado
dc.creatorBezerra, José Clecildo Barreto
dc.creatorBecker, Wilhelm
dc.creatorZelck, Ulrike E.
dc.date.accessioned2018-07-26T11:26:08Z
dc.date.available2018-07-26T11:26:08Z
dc.date.issued1997-06
dc.description.abstractThe freshwater snail Biomphalaria glabrata is an intermediate host of the trematode Schistosoma mansoni. However, some strains of B. glabrata are resistant to successful infection by S. mansoni larvae. The present work examines the profile of organic acids present in S. mansoni-resistant and -susceptible strains of B. glabrata, in order to determine whether the type of organic acid present is related to susceptibility. The organic acids were extracted from the hemolymph of two susceptible B. glabrata strains (PR, Puerto Rico and Ba, Jacobina-Bahia from Brazil), and from the resistant strains 13-16-R1 and 10R2, using solid phase extraction procedures followed by high performance liquid chromatography. The organic acids obtained were analyzed and identified by comparison with known standards. Pyruvate, lactate, succinate, malate, fumarate, acetate, propionate, ß-hydroxybutyrate and acetoacetate were detected in all hemolymph samples. Under standard conditions, the concentration of each of these substances varied among the strains tested and appeared to be specific for each strain. An interesting variation was the low concentration of pyruvate in the hemolymph of PR-snails. Only the concentration of fumarate was consistently different (p≤ 0.05) between resistant and susceptible strains.pt_BR
dc.identifier.citationBEZERRA, José Clecildo Barreto; BECKER, Wilhelm; ZELCK, Ulrike E. A comparative study of the organic content of the hemolymph of Schistosoma mansoni-resistant and susceptible strains of biomphalaria glabrata. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 3, p. 421-425, May/Jun. 1997.pt_BR
dc.identifier.doi10.1590/S0074-02761997000300021
dc.identifier.issn0074-0276
dc.identifier.issne- 1678-8060
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/15481
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectBiomphalaria glabratapt_BR
dc.subjectSusceptibilitypt_BR
dc.subjectHost-parasite interactionpt_BR
dc.subjectSchistosoma mansonipt_BR
dc.subjectOrganic acidspt_BR
dc.subjectResistancept_BR
dc.titleA comparative study of the organic content of the hemolymph of Schistosoma mansoni-resistant and susceptible strains of Biomphalaria glabratapt_BR
dc.typeArtigopt_BR

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Artigo - José Clecildo Barreto Bezerra - 1997.pdf
Tamanho:
137.14 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

IPTSP - Artigos publicados em periódicos