Detection of different types of papillomavirus and co-infection in cattle in the state of Goiás - Brazil
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2021
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El papilomavirus bovino (BPVs) es el agente etiológico de la papilomatosis bovina, una enfermedad que desencadena
verrugas en toda la piel, ubres, techos, genitales y en casos más severos puede desarrollar papilomas extensos, causar
neoplasias en el tracto digestivo y vejiga, ocasionar pérdidas de productividad. y pérdidas de ganado. En Brasil, la
aparición de la infección por BPV es relativamente común, pero la identificación de tipos virales aún es esporádica.
El presente estudio es un informe de investigación que tuvo como objetivo describir la ocurrencia de infecciones por
VBP en ganado lechero afectado por papilomatosis, a partir de las secuencias de nucleótidos del ORF L1, la
secuencia más conservada. Se analizaron 25 muestras de verrugas cutáneas de nueve bovinos diagnosticados
clínicamente como papilomatosis cutánea en el estado de Goiás, centro-oeste de Brasil. La amplificación se obtuvo en
11 muestras (papiloma) de diferentes bovinos. Las reacciones de PCR seguidas de secuenciación revelaron la
presencia de BPV-1 en el 60%, BPV-5 en el 40% y BPV-14 en el 20% de las muestras analizadas. Se verificó la
presencia de coinfección en el 60% de las muestras amplificadas. Estos datos sugieren que varios tipos de BPV
pueden infectar una lesión simultáneamente y demuestran la posibilidad de que la infección por BPV en el tejido
epitelial pueda ocurrir sin restricción a uno o dos tipos virales, lo que demuestra la diversidad genética de la región.
Hasta donde sabemos, este es el primer registro de tipificación de BPV de la región centro-occidental de Brasil. Este
análisis proporciona información importante para la investigación del virus del papiloma bovino (VBP) en Brasil.
Bovine papilomavírus (BPVs) is the etiological agent of bovine papillomatosis, a disease that triggers warts throughout the skin, udder, roofs, genitalia and in more severe cases can develop extensive papillomas, cause neoplasia in the digestive tract and bladder, cause losses in productivity and losses to livestock. In Brazil, the occurrence of BPV infection is relatively common, but the identification of viral types is still sporadic. The present study is a research report that aimed to describe the occurrence of BPV infections in dairy cattle affected by papillomatosis, based on the nucleotide sequences of the ORF L1, the most conserved sequence. Twenty-five samples of cutaneous wart from nine cattle clinically diagnosed as cutaneous papillomatosis were analyzed in the state of Goiás, central-western Brazil. Amplification was obtained in 11 samples (papilloma) from different cattle. PCR reactions followed by sequencing revealed the presence of BPV-1 in 60%, BPV-5 in 40%, and BPV-14 in 20% of the samples analyzed. The presence of coinfection was verified in 60% of the amplified samples. These data suggest that several types of BPV can infect a lesion simultaneously and demonstrate the possibility that BPV infection in epithelial tissue can occur without restriction to one or two viral types, demonstrating the region's genetic diversity. As far as we know, this is the first registry of typification of BPVs of the central-western region of Brazil. This analysis provides important information for bovine papillomavirus (BPV) research in Brazil.
Bovine papilomavírus (BPVs) is the etiological agent of bovine papillomatosis, a disease that triggers warts throughout the skin, udder, roofs, genitalia and in more severe cases can develop extensive papillomas, cause neoplasia in the digestive tract and bladder, cause losses in productivity and losses to livestock. In Brazil, the occurrence of BPV infection is relatively common, but the identification of viral types is still sporadic. The present study is a research report that aimed to describe the occurrence of BPV infections in dairy cattle affected by papillomatosis, based on the nucleotide sequences of the ORF L1, the most conserved sequence. Twenty-five samples of cutaneous wart from nine cattle clinically diagnosed as cutaneous papillomatosis were analyzed in the state of Goiás, central-western Brazil. Amplification was obtained in 11 samples (papilloma) from different cattle. PCR reactions followed by sequencing revealed the presence of BPV-1 in 60%, BPV-5 in 40%, and BPV-14 in 20% of the samples analyzed. The presence of coinfection was verified in 60% of the amplified samples. These data suggest that several types of BPV can infect a lesion simultaneously and demonstrate the possibility that BPV infection in epithelial tissue can occur without restriction to one or two viral types, demonstrating the region's genetic diversity. As far as we know, this is the first registry of typification of BPVs of the central-western region of Brazil. This analysis provides important information for bovine papillomavirus (BPV) research in Brazil.
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Saúde animal, Papiloma bovino, Gado bovino, Gado infectado, Sanidad animal, Papiloma bovino, Ganado bovino, Ganado infectado, Animal health, Bovine papilloma, Bovine cattle, Infected cattle
Citação
CHAGAS, Angelica de Lima das et al. Detection of different types of papillomavirus and co-infection in cattle in the state of Goiás - Brazil. Research, Society and Development, Vargem Grande Paulista , v. 10, n. 9, e45410918134, 2021. DOI: 10.33448/rsd-v10i9.18134. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18134. Acesso em: 3 jun. 2025.