Invasive pneumococcal infection in a healthy infant caused by two different serotypes
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2004-05
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We present a case of invasive pneumococcal infection in a healthy 10-month-old infant from whom Streptococcus
pneumoniae serotype 23F was isolated from the blood and serotype 23B was isolated from the
cerebrospinal fluid. Both serotypes were penicillin nonsusceptible. Pulsed-field gel electrophoresis analysis
demonstrated that the two serotypes had distinct DNA patterns, indicating that infection did not occur as a
result of capsular transformation but as a result of a mixed infection with two distinct pneumococcal serotypes.
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ANDRADE, Ana Lucia S. Sgambatti de et. al. Invasive pneumococcal infection in a healthy infant caused by two different serotypes. Journal of Clinical Microbiology, Washington, v. 42, n. 5, p. 2345-2346, 2004.