Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 ligandhi population
Carregando...
Data
2005-11
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
In the lungs of mice vaccinated with Mycobacterium bovis BCG, there was an accumulation of CD4 cells
expressing the activated effector phenotype CD44hi CD62 ligandlo (CD62Llo) which were capable of secreting
gamma interferon. Upon cell transfer, however, cells expressing a resting/naı¨ve phenotype (CD44lo CD62Lhi)
were capable of protecting the recipients from a virulent challenge infection, suggesting the emergence of T-cell
memory from within this subset.
Descrição
Palavras-chave
Citação
KIPNIS, Andre et al. Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 ligandhi population. Infection and Immunity, v. 73, n. 11, p. 7759-7764, 2005.