Prevalence of hepatitis C virus infection and associated factors among male illicit drug users in Cuiabá, Mato Grosso, Brazil

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dc.creatorNovais, Antônia Carlos Magalhães
dc.creatorLopes, Carmen Luci Rodrigues
dc.creatorReis, Nádia Rúbia da Silva
dc.creatorMartins, Regina Maria Bringel
dc.creatorSouto, Francisco José Dutra
dc.creatorSilva, Ágabo Macêdo Costa e
dc.date.accessioned2020-04-03T11:18:20Z
dc.date.available2020-04-03T11:18:20Z
dc.date.issued2009-09
dc.description.abstractIntravenous drug injection has been reported as the main risk factor for hepatitis C virus (HCV) infection. The aim of the present study was to describe the prevalence and the epidemiological profile of HCV infection among abusers of illegal injected and non-injected drugs in Cuiabá, state of Mato Grosso, Central Brazil. A cross-sectional study including 314 male drug users from eight detoxification centres was performed. Out of 314 subjects studied, 48 (15.2%) were intravenous drug users. Participants were interviewed and had blood samples taken and tested for the presence of anti-HCV antibodies. Positive samples were tested for the presence of HCV RNA. Genotyping was performed on HCV RNA-positive samples. The overall prevalence of anti-HCV antibodies was 6.4% (n = 20). Out of 20 anti-HCV antibody-positive subjects, 16 (80%) were also HCV RNA-positive. Genotype 1 predominated (75%), followed by 3a (25%). Subtype 1a was more common than 1b. HCV infection was more prevalent among intravenous drug users (33%) than non-injecting users (1.5%). Logistic regression analyses showed independent associations between HCV infection and intravenous drug use, imprisonment and increasing age. In the present study, inject- , imprisonment and increasing age. In the present study, injecting drug use was the factor most strongly associated to HCV infection and inhaling or sniffing did not represent an increased susceptibility to infection.pt_BR
dc.identifier.citationNOVAIS, Antônia Carlos Magalhães et al. Prevalence of hepatitis C virus infection and associated factors among male illicit drug users in Cuiabá, Mato Grosso, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 104, n. 6, p. 892-896, Sept. 2009.pt_BR
dc.identifier.doi10.1590/S0074-02762009000600012
dc.identifier.issn0074-0276
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/18967
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
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dc.subjectEpidemiologypt_BR
dc.subjectHepatitis C viruspt_BR
dc.subjectIllicit drug userspt_BR
dc.subjectHCV prevalencept_BR
dc.subjectHCV epidemiologypt_BR
dc.titlePrevalence of hepatitis C virus infection and associated factors among male illicit drug users in Cuiabá, Mato Grosso, Brazilpt_BR
dc.typeArtigopt_BR

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