Multidrug-resistant Escherichia coli isolated from a dog with a history of urolithiasis: case report
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2020
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Bacterial resistance is a reality in both human and veterinary health, it limits the therapeutic arsenal and
raises the costs of the patient’s treatment. A dog with signs of cystitis received treatment with 5mg/kg
enrofloxacin at three consecutive times, with low effectiveness. The presence of urethral uroliths was
identified and urohydropulsion was done. The animal presented a new obstruction, for which a cystotomy
was performed, but continued with signs of infection. Uroculture and antimicrobial susceptibility test were
then performed. Escherichia coli was identified, which was resistant to 13 antibiotics, being sensitive only
to piperacillin-tazobactam and amikacin. In the screening test for β-lactamase, the production of ESβL was
detected. The qPCR indicated the presence of the blaCTXm, blaDHA, blaOXA, blaIMP, blaTEM, blaGIM, blaSIM,
blaSPM and blaSME genes, which may lead to a phenotypic resistance profile for ampicillin, amoxicillin clavulanate, aztreonam, cefepime cefoxitin, cefuroxime, ceftazidime, ceftriaxone, imipenem, and
piperacillin-tazobactam. This case reaffirms the value that laboratory analysis adds to the diagnosis and
treatment of cystitis and urolithiasis, which can define the direction of evolution of the prognosis and the
speed at which the patient's health will be restored.
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Microbiologia veterinária, Análises clínicas, Antibióticos, Cistite, Veterinary microbiology, Clinical analysis, Antibiotics, Cystitis
Citação
MARTINS, I. J. et al. Multidrug-resistant Escherichia coli isolated from a dog with a history of urolithiasis: case report. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, v. 72, n. 3, p. 931-935, 2020. DOI: 10.1590/1678-4162-11203. Disponível em: https://www.scielo.br/j/abmvz/a/KtWvDcf5xPsczmHKhGd3tdk/. Acesso em: 3 jun. 2025.