Mycobacterium sherrisii lung infection in a brazilian patient with silicosis and a history of pulmonary tuberculosis

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dc.creatorAbrão, Carolina de Oliveira
dc.creatorAraújo Filho, João Alves de
dc.date.accessioned2019-01-21T10:44:51Z
dc.date.available2019-01-21T10:44:51Z
dc.date.issued2015
dc.description.abstractNontuberculous mycobacteria (NTM) diseases became relevant with the emergence and spread of HIV and are also related to lung infection in non-HIV individuals with structural lung diseases. Mycobacterium sherrisii is a NTM first characterized in 2004. Only a few cases have been reported. The aim of this case report is to describe the first detailed case of infection with M. sherrisii in a patient with silicosis and history of pulmonary tuberculosis. A 50-year-old HIV-negative white male, previous smoker, with silicosis and a history of treated pulmonary tuberculosis developed a worsening of cough and expectoration pattern, and two sputum samples were positive for acid-fast bacilli. Presumptive treatment for pulmonary tuberculosis was initiated with rifampin, isoniazid, pyrazinamide, and ethambutol, but, at month 5 of treatment, despite correct medication intake and slight improvement of symptoms, sputum bacilloscopy remained positive. Sputum cultures were positive Mycobacterium sherrisii. Treatment regimen was altered to streptomycin (for 2 months), ethambutol, clarithromycin, rifabutin, and trimethoprim-sulfamethoxazole. M. sherrisii should be considered a possible etiological agent of lung infections in patients with pneumoconiosis and history of tuberculosis.pt_BR
dc.identifier.citationABRÃO, Carolina de Oliveira; ARAÚJO FILHO, João Alves de. Mycobacterium sherrisii lung infection in a brazilian patient with silicosis and a history of pulmonary tuberculosis. Case Reports in Infectious Diseases, London, v. 2015, e498608, 2015.pt_BR
dc.identifier.doi10.1155/2015/498608
dc.identifier.issn2090-6625
dc.identifier.issne- 2090-6633
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/16749
dc.language.isoengpt_BR
dc.publisher.countryGra-bretanhapt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.titleMycobacterium sherrisii lung infection in a brazilian patient with silicosis and a history of pulmonary tuberculosispt_BR
dc.typeArtigopt_BR

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