Multisystem inflammatory disorder in children and kawasaki disease in the course of the SARS-COV-2 pandemic
Nenhuma Miniatura disponível
Data
2023-10-18
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Goiás
Resumo
After the onset of the new SARS-CoV-2 coronavirus pandemic, several countries reported
an increase in cases of Kawasaki Disease (KD) in the pediatric centers. KD, also called
mucocutaneous lymph node syndrome, presents as an acute, multisystem pediatric vasculitis
of unknown etiology. In this present study, we research to determine the influence of SARS CoV-2 on the manifestation of KD, the overlap with the so-called Multisystem Inflammatory
Syndrome in children (MIS-C) and to compare the main characteristics of these pathologies,
since this relationship was evidenced throughout the year of 2020 with pediatric patients
infected with coronavirus. To carry out the work, it was performed a systematic review in
accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses -
PRISMA. Articles published or pre-published in the PubMed and Scielo databases in 2020
were considered. A total of 924 scientific articles were identified, and after excluding duplicates
from the selection and data extraction, 52 remained for data comparison. None of the analyzed
parameters, such as clinical manifestation, age of affected patients, laboratory variants showed
a significant difference between the two groups, associated with the fact that there was no
increase in the number of KD cases in the absence of concomitant SARS-CoV-2 infection,
compared to pre-pandemic period. Thus, we conclude that MIS-C and KD concomitant with
Coronavirus Disease 2019 (COVID-19) were named without technical criteria given the
urgency in publishing information during the period of severity of the COVID-19 pandemic.
Descrição
Palavras-chave
COVID-19, SARS-CoV-2, Kawasaki disease, Multisystem inflammatory syndrome in children
Citação
MACHADO, Gabriela Stefany Lopes; LIMA, Vitor Carvalho; BICUDO, Lucilene Arilho Ribeiro. Multisystem inflammatory disorder in children and kawasaki disease in the course of the SARS-COV-2 pandemic. Revista de Patologia Tropical, Goiânia, v. 52, n. 3, p. 185-197, jul./set. 2023. DOI: 10.5216/rpt.v52i3.74534. Disponível em: https://revistas.ufg.br/iptsp/article/view/74534/40607. Acesso em: 27 dez. 2023.