Sapovirus in rectal and nasopharyngeal swab samples of children with symptoms of acute gastroenteritis

Silva, Thairiny Neres; Silva, Nathânia Dábilla Alves; Fiaccadori, Fabíola Souza; Cardoso, Divina das Dôres de Paula; Sousa, Teresinha Teixeira de; Almeida, Tâmera Nunes Vieira; Souza, Menira Borges de Lima Dias e

Sapovirus in rectal and nasopharyngeal swab samples of children with symptoms of acute gastroenteritis

Data

2018

Autores

Silva, Thairiny Neres

Silva, Nathânia Dábilla Alves

Fiaccadori, Fabíola Souza

Cardoso, Divina das Dôres de Paula

Sousa, Teresinha Teixeira de

Almeida, Tâmera Nunes Vieira

Souza, Menira Borges de Lima Dias e

Resumo

The study included 102 hospitalized children 0–72 months of age, with symptoms of acute gastroenteritis. One fecal and one nasopharyngeal swab sample were obtained from each child. Samples were screened for sapovirus and viral loads were determined. Sapovirus was detected in 18.6% of fecal samples and in 36.3% of nasopharyngeal swab samples. High viral loads were detected. Sapoviruses are important agents associated with acute gastroenteritis (AGE) worldwide. They belong to the Caliciviridae family, genus Sapovirus, are further classified into 7 genogroups (GI–GVII), from which 4 are known to infect humans (GI, GII, GIV and GV). The sapovirus particle is nonenveloped; it has icosahedral symmetry and the genetic material is composed of positive-sense linear single-stranded RNA.1 To date, sapovirus transmission route has been admitted to be the fecal–oral, by ingestion of contaminated food or water, through person-to-person contact, fomites and by the ingestion of aerosolized particles from vomit of infected individuals.2 For norovirus, another calicivirus, the respiratory transmission route has been speculated.3 The most common symptom associated with sapovirus infection is diarrhea, accompanied or not by vomit, fever and abdominal cramps.2 The main objective of this study was to investigate the presence of sapovirus in fecal samples and nasopharyngeal swab samples from children with AGE symptoms and to determine viral loads.

Citação

SILVA, Thairiny Neres et al. Sapovirus in rectal and nasopharyngeal swab samples of children with symptoms of acute gastroenteritis. Pediatric Infectious Disease Journal, Baltimore, v. 37, n. 4, p. e115-e116, 2018. DOI: 10.1097/INF.0000000000001833. Disponível em: https://journals.lww.com/pidj/fulltext/2018/04000/sapovirus_in_rectal_and_nasopharyngeal_swab.28.aspx. Acesso em: 9 dez. 2024.