Does the fertilization and reproduction success in iso 5/7 labor have a difference when compared to a conventional laboratory?
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2021
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To evaluate the tax of embryo’s development, embryo quality, chemical pregnancy and microbiological evaluation of the
means of embryos’ cultivation from patients attended at the Human Reproduction Laboratory of the conventional laboratory and after
the adjustment of RDC n° 23 de 2011, when it started to be classified as ISO 5/7 laboratory in 2013 and 2014. METHODOLOGY: This
control case study was developed at the LabRep/HC/UFG, located in Goiânia, Goiás, Brazil. It uses indirect observation as research
technique in order to analyze the records of women attended at the laboratory. From the total of women researched, 87 of them were
from the conventional laboratory and 191 were from the ISO 5/7 laboratory. The variables analyzed were: embryo’s development, βhCG
result, embryo quality and the assessed microbiological contamination of the means of embryos’ cultivation. The data was inserted
in the Epi-Info 33.2 program and it was analyzed in Bioestat 2.3. The groups were compared by odds ratio (OR) and chi-square with
p<5%. RESULTS: In ISO 5/7 laboratory, there was 74.1% of success in the embryo’s development while in the conventional laboratory,
there was 67.8% (OR: 1,30; IC: 0,47-3,61; χ2: 0,24; p: 0.81). Moreover, in ISO 5/7 laboratory, 96.6% of the generated embryos were A
or B, whereas 90.4% in the conventional laboratory (OR: 0,8906; IC: 0,27-2,89; χ2: 0,037; p: 0,85). The pregnancy success in ISO 5/7
laboratory was 22.8% and 36.2% in the conventional laboratory (OR: 1,92; IC: 0,81-4,52; χ2: 2,24; p: 0,13). CONCLUSION: There was
not a statistic difference between both laboratories.
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Laboratory quality in FIV, Embryo quality, Infertility, Human reproduction
Citação
GONTIJO, Érica Eugênio Lourenço et al. Does the fertilization and reproduction success in iso 5/7 labor have a difference when compared to a conventional laboratory? Human Reproduction Archives, São Paulo, v. 36, e000219-9, 2021. DOI: 10.4322/hra.000219. Disponível em: https://www.humanreproductionarchives.com/article/doi/10.4322/hra.000219. Acesso em: 30 abr. 2025.