Effects of integrated care on health outcomes in patients with diabetes in primary healthcare: a systematic review and meta-analysis protocol
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Diabetes is a leading global cause of morbidity and mortality among non-communicable diseases, with increasing prevalence and a disproportionate impact on low- and middle-income countries. Integrated care has emerged as a promising approach for addressing the challenges of diabetes management, thereby enhancing clinical outcomes and optimizing healthcare resource allocation. This protocol for a systematic review and meta-analysis aims to evaluate the effects of integrated care on clinical and health outcomes in individuals with diabetes who are followed up in primary care (PC):
● The method follows PRISMA-P 2015, PRISMA-S, and PRESS 2015 guidelines.
● A comprehensive search will be conducted in Scopus, Web of Science, PubMed, Embase, and CINAHL, supplemented by evidence mapping using Litmaps.
● Risk of bias will be assessed with validated tools, and the overall certainty of the evidence evaluated using GRADE.
Eligible studies will include those evaluating the effects of integrated care on clinical and health outcomes in individuals with diabetes treated in PC. The studies will be screened, and data will be synthesized through a meta-analysis. The findings may contribute to evidence-based public policies and the achievement of SDG-3. By encouraging the adoption of patient-centered approaches, strengthening interprofessional collaboration, and training aspects.
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COSTA, Woska Pires da et al. Effects of integrated care on health outcomes in patients with diabetes in primary healthcare: A systematic review and meta-analysis protocol. MethodsX, Amsterdam, v. 15, e103628, 2025. DOI: 10.1016/j.mex.2025.103628. Disponível em: https://www.sciencedirect.com/science/article/pii/S2215016125004728. Acesso em: 10 jul. 2026.