Metabolic effects of anthelminthic drugs in the larval stage of the cestode Taenia crassiceps, cysticercosis experimental model – a review

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2020

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Taenia crassiceps is an experimental model used for cysticercosis studies and has suffered metabolic analyzes regarding the effect of anthelminthic drugs. The metabolic analyses are useful tools to determine the drugs mode of action and the parasite`s survival mechanisms. The energetic pathways are good candidates for this kind of approach as they are essential for the parasite`s survival and adaptation to the environment. In this review we discuss the anthelminthic drugs mode of action and its metabolic impact on Taenia crassiceps cysticerci.

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Taenia crassiceps, Albendazole, Benzimidazole derivatives, Praziquantel, Nitazoxanide, Energy metabolism

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VINAUD, Marina C.; AMBROSIO, Javier. Metabolic effects of anthelminthic drugs in the larval stage of the cestode Taenia crassiceps, cysticercosis experimental model – a review. Acta Trópica, Amsterdam, v. 206, e105448, 2020. DOI: 10.1016/j.actatropica.2020.105448. Disponível em: https://www.sciencedirect.com/science/article/pii/S0001706X19315414?via%3Dihub. Acesso em: 20 fev. 2025.