Decline in hepatitis B and C prevalence among hemodialysis patients in Tocantins, northern Brazil
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2018
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Infection control measures have been responsible for a decline in the prevalence of
hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in hemodialysis patients. In
Brazil, these measures have been in place since 1996. The aim of this study was to evaluate
the current HBV and HCV epidemiology among hemodialysis patients in the State of
Tocantins comparing them with those found 14 years ago. There was a significant decline
in hepatitis B surface antigen (HBsAg) and anti-HCV prevalence from 4% and 13% in 2001
to 0.8% and 2.8% in 2014-2015, respectively (p < 0.05). Variables related to hemodialysis
environment such as working shift and length of time on hemodialysis treatment were no
longer associated to HCV and HBV exposure in 2014-2015. A high prevalence of self-reported
hepatitis B vaccination was observed in both periods, but only 30% of the individuals showed
serological profile of effective previous immunization, suggesting a low compliance with
surveillance of hepatitis B immunization in hemodialysis centers. The significant decline
in viral hepatitis B and C prevalence in hemodialysis patients in Tocantins underscores the
importance of infection control measures, but the low frequency of protective serological
profile after immunization against hepatitis B points to the need for greater vigilance of the
patients’ vaccination.
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Epidemiology viral hepatitis, Dialysis, Hepatitis B, Hepatitis C, Hemodialysis
Citação
CORDEIRO, Valéria Maciel et al. Decline in hepatitis B and C prevalence among hemodialysis patients in Tocantins, northern Brazil. Revista do Instituto de Medicina Tropical de São Paulo, v. 60, e36, 2018. DOI: 10.1590/S1678-9946201860036. Disponível em: https://www.scielo.br/j/rimtsp/a/nk8t5PYtPPN8gLZgDbBghbz/. Acesso em: 8 abr. 2025.