Diagnosis of chromoblastomycosis: an historical review
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Data
2022-07-21
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Universidade Federal de Goiás
Resumo
Chromoblastomycosis is a skin infection caused by dematiaceous fungi, characterized by
a verrucous plaque on the limbs. It mainly affects rural workers in tropical countries. The
purpose of this review is to identify how the diagnostic methods used in the propaedeutic of
chromoblastomycosis emerged and were developed. The MeSH terms “chromoblastomycosis”
or “chromomycosis” or “verrucous dermatitis” and “diagnosis” were used to search articles
indexed in MEDLINE and LILACS databases. The description of a first-time-used method in
diagnosing chromoblastomycosis or modifications and innovations in an existing technique
was the criteria used to deem the article eligible. The first methods described in diagnosing
chromoblastomycosis were histopathological examination and culture, which characterizes
and defines the disease in the early 20th century. Subsequently, they were described as direct
microscopic examination, fine needle aspiration for cytology, electron microscopy, serology,
molecular tests, scintigraphy, nuclear magnetic resonance and dermoscopy. Tests based on the
direct identification of the fungus through biopsy, culture, or direct microscopy are the oldest
and more employed methods for diagnosing chromoblastomycosis. The polymerase chain
reaction was introduced in the last few decades and is a promising technique. Dermoscopy of
chromoblastomycosis shows blackish red dots and white and pink areas along with scaling.
Other techniques, such as serology and skin testing for delayed-type hypersensitivity, have not
been incorporated into clinical practice.
Descrição
Palavras-chave
Chromoblastomycosis, Diagnosis, Review
Citação
BORGES, Jules Rimet; EDA, Yann Victor Medeiros; IANHEZ, Mayra; GARCIA - ZAPATA, Marco Tulio Antonio. Diagnosis of chromoblastomycosis: an historical review. Journal of Tropical Pathology, Goiânia, v. 51, n. 2, p. 97-15, July 2022. Disponível em: https://revistas.ufg.br/iptsp/article/view/71026. Acesso em: 4 ago. 2022.