Circulation profile of respiratory viruses in symptomatic and asymptomatic children from Midwest Brazil
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Data
2020
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Resumo
Acute respiratory infection (ARI) is a major cause of morbidity and mortality worldwide. Most of these infections are caused by
viruses. Infections pose as important triggers of acute episodes of chronic respiratory diseases (CRD). This study sought to
evaluate the frequency and circulation profile of respiratory viruses among ARI symptomatic patients and completely asymp tomatic children in Midwest Brazil. The study enrolled symptomatic children with and without ARI symptoms. During 1 year,
225 nasal respiratory samples were obtained from patients aged 4–14 years old. The samples were screened by multiplex nested PCR for 16 common respiratory viruses. From 225 samples, 42 had at least one virus detected. Samples from four different
patients had multiple viruses detected. The viral detection rate in symptomatic (20.1%) and asymptomatic patients (14.8%)
showed no significant difference. The most frequent viruses detected were rhinovirus (28.6%), FLUA (11.9%), adenovirus
(11.9%), human bocavirus (HBoV) (11.9%), and respiratory syncytial virus (RSV) antigenic group A (9.5%). Monthly detection
rate was higher during the rainy season. RSVs were detected during the months with higher rainfall indexes and higher air
humidity, while FLU and HBoV were detected during the winter months. The obtained results reinforce the importance of viral
pathogens in pediatric population, emphasizing similar viral occurrence in symptomatic and asymptomatic children.
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Respiratory viruses, Asymptomatic children, Circulation profile, Multiplex PCR
Citação
CASTRO, Italo Araujo et al. Circulation profile of respiratory viruses in symptomatic and asymptomatic children from Midwest Brazil. Brazilian Journal of Microbiology, Rio de Janeiro, v. 51, n. 4, p. 1729-1735, 2020. DOI: 10.1007/s42770-020-00368-0. Disponível em: https://link.springer.com/article/10.1007/s42770-020-00368-0. Acesso em: 6 dez. 2024.