Hepatic involvement in paracoccidioidomycosis

Abstract

Paracoccidioidomycosis involves the liver and/or the bile ducts in a considerable number of patients with the acute disseminated form of the disease in the lymphatic abdominal type. It may produce fatty degenerative changes in the hepatic parenchyma, acute hepatitis, chronic granulomatous hepatitis, moderate portal fibrosis and occasionally marked necrosis. These changes are accompanied by jaundice. Frequently obstrutive extrahepatic jaundice dominates the clinicai manifestations