Low prevalence, low immunization and low adherence to full hepatitis B vaccine scheme and high-risk behaviors among crack cocaine users in central Brazil
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2017
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Resumo
Crack cocaine users represent a target group for hepatitis B vaccina tion. We evaluate the HBV epidemiology, immunization status and compliance with
a super-accelerated vaccination schedule among in-treatment crack cocaine users
in central Brazil. Six hundred in-treatment crack cocaine users were interviewed,
and serum samples were tested for HBV markers. A super-accelerated vaccination
schedule of HBV vaccine was offered to all susceptible crack cocaine users. In total,
7.0% of those tested had at least one positive marker of HBV exposure. Age, use of
crack cocaine through improvised pipe, exchange of sex for money/drugs and pre vious sexually transmitted infections (STIs) were predictors of HBV exposure. One
hundred six (17.7%) individuals showed a serological profile of hepatitis B vacci nation. Of these, 54.7% were less than 25 years old, and only 13% of individuals
were more than 35 years old. Although 91.8% of crack users accepted the first
vaccine dose, only 21.7% received all three doses. Of the 23 crack cocaine users who HBs titers. Premature termination of treatment was the most common reason for not
receiving the full vaccine series. Despite the low prevalence of HBV exposure among
in-treatment crack cocaine users in central Brazil, the low rate of immunization and
the high frequency of high-risk behaviors highlight the potential for crack users to
acquire and disseminate this infection and therefore maintain the viral reservoir.
Health practitioners need to keep this in mind, taking advantage of all opportunities
to access this population and vaccinate against HBV.
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Hepatitis B, Crack cocaine, Epidemiology, Hepatitis B vaccine
Citação
SILVA, Leandro N. da et al. Low prevalence, low immunization and low adherence to full hepatitis B vaccine scheme and high-risk behaviors among crack cocaine users in central Brazil. Journal of Infection and Public Health, Oxford, v. 10. n. 1, p. 76-83, 2017. DOI: 10.1016/j.jiph.2016.02.010. Disponível em: https://www.sciencedirect.com/science/article/pii/S1876034116300090?via%3Dihub. Acesso em: 7 mar. 2025.