Monitoring the circulation of rotavirus among children after the introduction of the Rotarix tm vaccine in Goiânia, Brazil

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dc.creatorBorges, Ana Maria Tavares
dc.creatorSouza, Menira Borges de Lima Dias e
dc.creatorFiaccadori, Fabíola Souza
dc.creatorCardoso, Divina das Dores de Paula
dc.date.accessioned2018-07-19T11:53:19Z
dc.date.available2018-07-19T11:53:19Z
dc.date.issued2011-06
dc.description.abstractThe epidemiological features of rotavirus A (RVA) infection differ between children from developing and de- veloped countries which could result in differences in vaccine efficacy around the world. To evaluate the impact of RotarixTM on RVA prevalence, we monitored RVA genotypes circulating in Goiânia by monitoring virus in faecal samples from children that had or had not been previously vaccinated. From February-November of 2008, 220 faecal samples were collected from children in seven day-care centres. RVA detection was performed by two meth- odologies and the results were confirmed by polyacrylamide gel electrophoresis. From the 220 samples, eight were RVA-positive (3.6%) and five were from children that had received either one or two doses of the vaccine. All positive samples were collected from children with diarrhoea during August and September. Genotyping of the RVA charac- terised five of the viral samples as genotype G2P[4] and one as G8P[4], suggesting that G2P[4] was the predominant circulating genotype in Goiânia during the study. The fact that vaccinated children were also infected by RVA sug- gests that the vaccine does not fully protect against infection by the G2[P4] RVA genotype.pt_BR
dc.identifier.citationBORGES, Ana Maria Tavares; SOUZA, Menira Dias e; FIACCADORI, Fabíola Souza ; CARDOSO, Divina das Dôres de Paula. Monitoring the circulation of rotavirus among children after the introduction of the Rotarix tm vaccine in Goiânia, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 4, p. 499-501, jun. 2011.pt_BR
dc.identifier.doi10.1590/S0074-02762011000400018
dc.identifier.issn0074-0276
dc.identifier.issne- 1678-8060
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/15422
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectRotaviruspt_BR
dc.subjectEpidemiologypt_BR
dc.subjectRotavirus infectionspt_BR
dc.subjectRotavirus vaccinept_BR
dc.titleMonitoring the circulation of rotavirus among children after the introduction of the Rotarix tm vaccine in Goiânia, Brazilpt_BR
dc.typeArtigopt_BR

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