Soropositividade ao PGL-I em um centro de reintegração para pessoas atingidas pela hanseníase e diferentes regiões do Município de Anápolis-Goiás

Resumo

Objective: To carry out a comparative serological evaluation to the Phenolic Glycolipid antigen-I (PGL-I), using the ML Flow test, among residents of an institution coordinated by the movement for reintegration of people affected by leprosy to that found among adjacent areas and geographically distant from the city of Anápolis, in the state of Goiás, in order to collaborate in the seroepidemiological description of leprosy. Methods: This was an exploratory, observational, cross-sectional, non-controlled, non-randomized prevalence survey. It involved application of the ML Flow immunochromatographic test for detection of anti-PGL-I antibodies, developed by the Institute of Tropical Pathology and Public Health of the Federal University of Goiás, in addition to a semi-structured questionnaire directed to the social determinants of the disease. Data were collected in 2018 by convenience sampling. Results: 79 people participated, being 19 inmates of the institution (Group 1), 20 surrounding residents (Group 2) and 40 inhabitants of distant areas of the city (Group 3), being detected IgM immunoglobulins directed to the antigen in 10.5%, 10% and 2.5%, respectively. Higher seropositivity was observed in the institution and nearby areas, in contrast to the distant regions of the city. However, the data obtained suggest similar seroprevalence to endemic regions and is justified by the historical configuration of the neighborhood. In addition, the current cases reported in the municipality are diffusely distributed throughout the city limits, without exceptional geographical restriction. Conclusion: Serological clarification and information about the pathology favor the elimination of marginalization and stigmas imposed on individuals who once had the disease or who are under conditions of social vulnerability sheltered by the institution.

Descrição

Palavras-chave

Hanseníase, Mycobacterium Leprae, Preconceito, Estigma Social, Sorologia

Citação

LOPES, Leonardo Queiroz et al. Soropositividade ao PGL-I em um centro de reintegração para pessoas atingidas pela hanseníase e diferentes regiões do Município de Anápolis-Goiás. Brazilian Journal of Health Review, Curitiba, v. 4, n. 2, p. 6834-6845, 2021. DOI: 10.34119/bjhrv4n2-231. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/27335.Acesso em: 11 abr. 2025.