Trends of T.cruzi infection based on data from blood bank screening
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Data
1990
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Resumo
Between October 1988 and April 1989 a cross-sectional survey was carried out in six out of eight blood banks of Goiania, Central Brazil. Subjects attending for first-time blood donation in the mornings of the study period in = 1358) were intervie-wed and screened for T. cruzi infection as a part of a major study among blood donors. Tests to anti-T. cruzi antibodies were performed, simultaneously, by indirect hemagglutination test (IHA) and complement fixation test (CFT). A subject was considered seropositive when any one of the two tests showed a positive result. Information on age, sex, place of birth, migration and socio-economic level was recorded. Results from this survey were compared with seroprevalence rates obtai-ned in previous studies in an attempt to analyse trend of T. cruzi infection in an endemic urban area. The overall seroprevalence of T. cruzi infection among first-time donors was found to be 3.5% (95% confidence interval 2.5%-4.5% ). The seroprevalence rate increased with age up to 45 years and then decreased. Migrants from rural areas had higher seroprevalence rates than subjects from urban counties (1.8%-16.2% vs. 0%-3.6%). A four fold decrease in prevalence rates was observed when these rates were compared with those of fifteen years ago. Two possible hypo-theses to explain this difference were suggested: 1. a cohort effect related with the decrease of transmission in rural areas and/or 2. a differential proportion of people of rural origin among blood donors between the two periods. The potential usefulness of blood banks as a source of epidemiological information to monitor trends of T. cruzi infection in an urban adult population was stressed.
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Trypanosoma cruzi, Blood bank screening, Cross-sectional survey
Citação
ZICKER, Fábio et. al. Trends of T.cruzi infection based on data from blood bank screening. Revista de Saúde Pública, São Paulo, v. 32, n. 2, p. 132-134, 1990.