Atividade tripanocida in vivo de Stryphnodendron adstringens (barbatimão verdadeiro) e Caryocar brasiliensis (pequi)

Resumo

Crude extracts from barks of Stryphnodendron adstringens and Caryocar brasiliensis, native species of Cerrado, have been screened at 400 ppm for antiparasitic activ- ity against Trypanosoma cruzi. Mice were inoculated with 1x10 4 parasites, after 24 h they were treated with one day dose ex- tracts during ten days. The trypanosomicidal activity was evalu- ated each 48 h until animals death. The extracts of S. adstringens and C. brasiliensis decreased significantly the number of para- sites in the blood.

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Citação

HERZOG-SOARES, Joanna D’Arc; ALVES, Rosangela K.; ISAC, Eliana; BEZERRA, José Clecildo B.; GOMES, Maria H.; SANTOS, Suzana C.; FERRI, Pedro H. Atividade tripanocida in vivo de Stryphnodendron adstringes (Barbatimão verdadeiro) e Caryocar brasiliensis (Pequi). Revista Brasileira de Farmacognosia, Maringá, v. 12, supl. 1, 2002.