Programa de Pós-graduação em Nutrição e Saúde
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Item Potencial prebiótico dos resíduos de puçá (Mouriri elliptica Mart.) e gabiroba (Campomanesia adamantium (Cambess.)) O. Berg em diferentes espécies de micro-organismos probióticos(Universidade Federal de Goiás, 2021-08-30) Barbosa, Jéssica Pereira; Tette, Patrícia Amaral Souza; http://lattes.cnpq.br/2108602143480173; Tette, Patrícia Amaral Souza; Martins, Eliane Maurício Furtado; Bastos, Sabrina CarvalhoPuçá (Mouriri elliptica Mart) and gabiroba (Campomanesia adamantium (Cambess.) O. Berg) are fruits from Cerrado Savannah with high nutritional quality and content of bioactive compounds proved to be beneficial to health. Due to their favorable characteristics for industry food applicability, the fruit processing can generate a significant volume of residues, mainly composed by peel and seeds, that are nutritionally relevant and can be added into human food and may present prebiotic potential. Therefore, the aim of this study was to investigate the prebiotic potential of freeze-dried residues from puçá (PR) and gabiroba (GR). For this, the residues characterization was carried out through physicochemical parameters, phenolic compounds and sugar contents. The fermentative capacity of Lactobacillus acidophilus LA-05, Lactobacillus casei L-26 and Bifidobacterium animalis subsp. lactis BB-12 and the prebiotic activity score (PAS) in the presence of two strains of Escherichia coli were evaluated. PR and GR presented high levels of dietary fiber (55.70% and 65.29%), lipids (18.48% and 13.05%), and PR showed considerable carbohydrate content (12.90%). Substantial content of phenolic compounds were found in PR and GR: catechin (44.71 mg.L-1 ± 1.49 in GR), procyanidin B2 (12.97 mg.L-1 ± 0.33 in PR and 13.88 mg.L-1 ± 0.72 in GR). Cultivation of the probiotics in media with PR and GR (20 g.L-1) showed high bacterial counts (9.27 - 13.23 log CFU.mL-1), decreased pH and positive PAS for all strains. Both residues were used as a carbon source for the growth of the probiotic bacteria over the incubation time. The phenolic compounds of the both residues may be involved on the mechanism of the positive prebiotic activity observed. Therefore, the residues from puçá and gabiroba are potential prebiotic ingredients for use in formulation of foods, increasing the nutritional value and reducing the negative impacts on the environment that can caused by their discard.Item Consumo alimentar e expressão do miR-375 de pacientes com carcinoma espinocelular de cabeça e pescoço(Universidade Federal de Goiás, 2019-02-22) Ferreira, Tathiany Jéssica; Cominetti, Cristiane; http://lattes.cnpq.br/3143023553465749; Vencio, Eneida Franco; http://lattes.cnpq.br/0539115059597412; Horst, Maria Aderuza; http://lattes.cnpq.br/4145824009736834; Horst, Maria Aderuza; Saddi, Vera Aparecida; Vilela, Ana Amélia FreitasObjective: To determine the association between the miR-375 expression pattern and the dietary intake of patients in pre-treatment head and neck squamous cell carcinoma (HNSCC). Material and methods: This is an observational cross-sectional study type. Were included 67 patients with a diagnosis of (HNSCC), both sexes, from 19 to 80 years. The variables investigated were: age, sex, profession and ethnicity; use of alcohol and tobacco, food consumption; tumor staging and anatomical site. The instrument used to evaluate food intake was the food frequency questionnaire (FFQ) from the ELSA-BRAZIL study. The intake of energy, macronutrients and micronutrients, as well as food groups, were evaluated. The expression of miR-375 was evaluated by reverse transcription followed by real-time polymerase chain reaction (RT-qPCR), in an oral rinse sample. Results: The sample comprised 43.3% of the patients with the neoplasia in the oropharynx cavity; 37.3% in the oral cavity, and 19.4% in the hypopharynx / larynx. Between the patients evaluated by anatomical sites, there was no significant difference between dietary intake of energy, nutrientes, and food groups. Also, there was no difference in miR-375 expression profile between anatomical sites. In addition, the expression of miR-375 was positively associated with the consumption of energy, iron, magnesium, selenium, vitamin B1, vitamin E, and alcohol. However, it was negatively associated with the intake of carbohydrates, cholesterol, phosphorus, and folate. Conclusions: The findings indicate a possible association between feeding and expression of miR-375, considered a tumor suppressor in head and neck neoplasms.Item Discursos de professores e de coordenadores pedagógicos sobre alimentação escolar(Universidade Federal de Goiás, 2018-02-28) Oliveira, Giovanna Angela Leonel; Monego, Estelamaris Tronco; http://lattes.cnpq.br/0917323812776538; Mortoza, Andrea Sugai; http://lattes.cnpq.br/4896920176590532; Martins, Karine Anusca; http://lattes.cnpq.br/8697079749159115; Martins, Karine Anusca; Lima, Jacqueline Rodrigues de; Tavares, Naraiana de OliveiraIntroduction: The Brazilian School Feeding Program (PNAE) is a public policy that provides a guarantee of Food and Nutrition security, through the supply of school drinks and Food and Nutrition Education) actions. The teachers of the school's specialization school law specialize in the PNAE, which in turn is a teacher and pedagogical coordinator in the implementation of the PNAE. Objective: To unveil the discourses of the teacher and the pedagogical coordinator in the context of school education. Methods: Qualitative research. Teachers and pedagogical coordinators of schools assisted by PNAE were interviewed in all Brazilian regions. The base was made through the draw, among those that are part of the actions of Food and Nutrition Education. The study was part of the discourses that revealed the continuation of what they knew about school education; the role of school feeding in the educational process; compliance directions and joint activities with the Program's nutritionist. The sessions were analyzed and analyzed by the Collective Subject Discourse technique, classified in playful, polemical or authoritarian discourses and interpreted by Theory of Social Representations. Results and discussion: Schools from 57 Brazilian municipalities were visited. Most of the speeches are reproductive of the assistance model still present in the educational base. It was identified there is a course on the understanding of pedagogical coordinators and teachers about a feeding in the school. In addition, it is emphasized that the obstacles to the integration of nutrition management are a lack of guidelines on the management of the articulation with the technical support to the PNAE in the municipality. Considerations: Despite all the advancements, the program is still important; the processes of training, freedom and citizenship of the actors perform in the school, with a view to collaboration with a qualified qualification of the policy at the local level.Item Potencial prebiótico da polpa de baru(Universidade Federal de Goiás, 2022-08-29) Santos, Aline Medeiros Alves; Naves, Maria Margareth Veloso; http://lattes.cnpq.br/6563181057140270; Naves, Maria Margareth Veloso; Andrade, Roberta Melquiades Silva de; Egea, Mariana Buranelo; Batista, Ângela Giovana; Mendonça, SimoneBaru (Dipteryx alata Vog.) is a fruit native to the Cerrado biome consisting of a thin peel, a fibrous pulp and a woody endocarp, which covers the nut. During the processing of the fruit for nut extraction, the baru pulp is not used by the agro-industry, and its chemical composition and health effects are poorly known. Some studies indicate that baru pulp has dietary fiber and polyphenols, which have prebiotic activity. The growing interest in health and well-being promoting foods from alternative sources, such as agro-industrial by-products, and the social, economic and environmental impacts generated by the use of these by-products justify the search for new prebiotics. Thus, the aims of this study were: to elaborate and publish a systematic review on the prebiotic effect of polyphenols; to carry out and publish a critical review of the literature on the nutritional and functional characteristics of baru; in addition to evaluate the chemical composition of baru pulp and to investigate its effects on the growth and metabolism of probiotics, and on the human colonic microbiota. According to the systematic review, there is strong evidence from preclinical studies that some polyphenols can stimulate the growth of beneficial gut bacteria and increase the production of short-chain fatty acids. The critical review on baru showed the nutritional and functional potential of baru pulp, as well as the gaps in the literature on its chemical composition. Results of the empirical research show that baru pulp has a high content of insoluble fibers and phenolic compounds, mainly hesperidin. Baru pulp stimulated the growth and metabolism of Bifidobacterium animalis subsp. lactis BB-12, Lactobacillus acidophilus LA-05 and Lacticaseibacillus casei L-26. Furthermore, significant beneficial changes were induced by the digested baru pulp on colonic microbiota, with an increase in the abundance of Lactobacillus-Enterococcus, Bifidobacterium and Bacteroides-Prevotella, and the production of lactate and short-chain fatty acids, and pH reduction. Therefore, baru pulp has potential prebiotic properties to be confirmed in preclinical and clinical studies, and to be explored as an ingredient in the formulation of new health-promoting foods.Item Equivalência semântica, validação e reprodutibilidade da escala de angústia de sede (thirst distress scale) para pacientes em hemodiálise(Universidade Federal de Goiás, 2019-03-01) Sugizaki, Clara Sandra de Araújo; Freitas, Ana Tereza Vaz de Souza; http://lattes.cnpq.br/5288011784889591; Peixoto, Maria do Rosário Gondim; http://lattes.cnpq.br/6813295858384008; Peixoto, Maria do Rosário Gondim; Naghettini, Alessandra Vitorino; Rodrigues, Juliana Cordeiro Dias; Silva, Lara Lívia Santos da; Stringhini, Maria Luiza FerreiraINTRODUCTION: Ingestion of fluid from hemodialysis patients is directly related to thirst and, consequently, to increased weight gain in the dialysis range. Interdialytic weight gain (GPID) greater than 2.5 kg or 4.5% of dry weight can cause complications such as hypertension, congestive heart failure and even death. In view of the importance of thirst suffering for non-adherence to water restrictions, a valid and reliable instrument is needed to measure and treat thirst. OBJECTIVES: To validate the Portuguese version of the Thirst Distress Scale (TDS); to identify fluid handling strategies to meet water constraints. METHODOLOGY: Methodological study of scales validation. The study took place in three stages. In the first one, the semantic equivalence was performed, which followed the flow of translations, back translation and cultural adaptation of language to obtain a scale in the Portuguese language that was applied in a pre-test in 50 patients. After the pre-test, the validation stage was started, in which the definitive scale was applied in 126 patients from two hemodialysis clinics in the city of Goiânia – Goiás, Brazil. The third step was the verification of reproducibility, in which 70 of the 126 initial patients answered the same questionnaire again. RESULTS: The Thirst Distress Scale – 3ortuguese (TDS-PT) scale was validated psychometrically for Portuguese. The final version was well understood by the sample, retained the elements of semantic equivalence between the terms. The six items on the scale had good internal consistency of 0.84 with each other. The scales presented a correlation (r = 0.7, p <0.001) and agreement (kappa = 0.44, p <0.001) with the Visual Analogue Scale (EVA). Consumption of ice cubes, water swallowing without swallowing and marking gum were fluid management strategies that were associated with less distress in relation to thirst. CONCLUSION: The TDS-PT scale was adequate in relation to its psychometric validation qualities, with good internal consistency between the items, which indicates reliability of the construct. The use of TDS-PT, adapted and validated in this study, may facilitate the clinical reasoning and fluid management process of this population. In addition, it will allow the identification of the diagnosis of thirst anxiety, since it has proved to be a reliable, valid and efficient instrument capable of assessing the phenomenon that is proposed to measure (thirst anxiety)