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Item type: Item , Formulações à base de vegetais em pó para aplicação em nutrição enteral domiciliar(Universidade Federal de Goiás, 2025-09-30) Almeida, Graciele Magda de; Egea, Mariana Buranelo; http://lattes.cnpq.br/2608350008080000; Egea, Mariana Buranelo; Ferreira, Tânia Aparecida Pinto de Castro; Lemes, Ailton Cesar; Lima, Bernardo Romão de; Lima, Mayra Conceição Peixoto MartinsEnteral nutrition (EN) is considered a therapeutic strategy for individuals with a functioning gastrointestinal tract but unable to maintain sufficient food intake for the maintenance or recovery of nutritional status. Formulations can be industrialized, in powder or liquid form, or homemade, prepared from fresh foods. Natural foods significantly influence the intestinal microbiota due to vitamins, minerals, fibers, and bioactive compounds, such as polyphenols, with recognized prebiotic action. An alternative to homemade formulations is the use of dehydrated powdered foods. In this context, food science and technology seeks to develop formulations based on natural foods, with defined composition, microbiological stability, and technological suitability, ensuring food and nutritional sovereignty in enteral therapy. The study aimed to: evaluate patients undergoing home enteral nutritional therapy (HENT) regarding their perceptions of their feeding method and its impact on quality of life; analyze the microbiological quality of the homemade formulations used; and develop a solid powder product from dehydrated vegetables, characterizing it in terms of physicochemical, chemical, technological, and rheological parameters. The work was structured into four interdependent chapters, which complement each other in building a comprehensive view of home enteral nutritional therapy (HENT). Chapter I presents a literature review on HENT, its evolution, clinical applications, challenges, and perspectives in the care of patients with specific nutritional needs. In Chapter II, a systematic review complementary to the central theme was conducted, entitled "Probiotics: a little help for enteral nutritional therapy in critically ill adults". The objective was to gather evidence on the clinical effects of probiotic administration in patients undergoing EN. Twenty-one studies were analyzed involving patients in different care settings—intensive care units, wards, and homes—with control groups using isolated enteral nutrition or placebo. The results indicated consistent clinical benefits associated with the use of probiotics, including reduced hospitalization time, improved gastrointestinal function, lower incidence of antibiotic-associated diarrhea, and reduced inflammatory and immunological responses, as well as a decrease in ventilatorassociated pneumonia. No significant adverse effects were observed, reinforcing the safe and beneficial potential of this adjuvant strategy to enteral nutrition. Chapter III presents the cross-sectional study entitled “Nutritional and microbiological aspects of formulations and the impact of the use of home enteral nutritional therapy on the quality of life of patients”. Twenty-two patients on home enteral nutritional therapy (HENT) were evaluated, predominantly elderly, bedridden, and dependent, with gastrostomy being the most frequent method (72.7%). Industrialized formulations were the most used (54.5%), while homemade formulations accounted for 27.3%, characterized by low nutritional diversity and risk of contamination resulting from home preparation. The main complications reported were diarrhea (72.7%) and tube obstruction (77.3%). Despite the difficulties, 91% of the participants classified their quality of life as acceptable. The study highlighted the need for multidisciplinary support and continuous nutritional education to optimize the safety and effectiveness of HENT. Finally, Chapter IV describes the technological development of a plant-based powder product formulated for use in enteral nutrition. It was developed from nine plant-based ingredients including kale, ora-pro-nobis, chickpeas, flaxseed, beetroot, turmeric, almond, pumpkin seeds, and sweet potato. Physicochemical (moisture, pH, soluble solids, ash), chemical (proximal composition and energy value), technological (water absorption, solubility, stability and emulsifying activity) and rheological analyses were conducted. Two formulations were developed using a simplex-centroid factorial design, prioritizing protein and lipid content and caloric density. F1, intended for nasoenteral tubes and other routes without filtration, contained 63.94 g/100 g of carbohydrates, 33.86 g/100 g of fiber, 18.60 g/100 g of protein, 5.31 g/100 g of lipids and 377.95 kcal. F2, intended for bolus administration via gastrostomy, contained 46.00 g/100 g of carbohydrates, 9.70 g/100 g of fiber, 21.23 g/100 g of protein, 24.07 g/100 g of lipids and 485.55 kcal. According to ANVISA (2015), F1 can be classified as normoprotein, hypercarbohydrate, hypolipid and rich in fiber, while F2 is normoprotein, hypocarbohydrate and hyperlipid. In administration tests, F1 showed gravitational infusion between 52 and 72 drops/minute, and, in bolus administration, a slow infusion of 60 mL in approximately four minutes, without resistance to the syringe. Both formulations maintained adequate stability, homogeneity, fluidity and osmolality. The results reinforce the relevance of multidisciplinary care and nutritional education for patients, caregivers, and family members, promoting safety and adherence to treatment. The developed formulations proved to be nutritionally viable, approaching the recommendations for enteral nutrition and valuing the use of less processed foods. It is concluded that it is possible to develop powdered products from dehydrated vegetables, with technological stability and nutritional adequacy, constituting an innovative and sustainable alternative for home enteral nutrition. Together, the results of this thesis contribute to the advancement of knowledge about enteral nutritional therapy and reinforce the importance of the integration between science, clinical practice, and technological innovation in the search for safe food solutions aimed at home care.Item type: Item , Análise da interface em diferentes sistemas de pinos de fibra de vidro e em técnicas de cimentação por meio de um novo software de tomografia computadorizada de feixe cônico(Universidade Federal de Goiás, 2022-06-28) Cruvinel Filho, Jorge Luiz de Oliveira; Rocha, Sicknan Soares da; http://lattes.cnpq.br/8256226109956656; Estrela, Carlos; http://lattes.cnpq.br/4939545848747102; Estrela, Carlos; Alencar, Ana Helena Gonçalves de; Paula, Juliê Marra deEmbargadoItem type: Item , Diagnóstico situacional e análise preditiva das demandas de um Núcleo de Telemedicina e Telessaúde, Brasil (2015-2022)(Universidade Federal de Goiás, 2024-02-28) Silveira, Camila Costa da; Lopes, Flavio Marques; http://lattes.cnpq.br/1423301895802989; Lopes, Flavio Marques; http://lattes.cnpq.br/1423301895802989; Dewulf, Nathalie de Lourdes Souza; http://lattes.cnpq.br/1244479719591748; Alcântara, Keila Correia de; http://lattes.cnpq.br/3089303305362001Embargado.Item type: Item , Abordagem Não-Linear de Redução de Dimensionalidade em Duas Etapas aplicada à classificação de engajamento em Redes Sociais(Universidade Federal de Goiás, 2025-10-14) Vieira Sobrinho, José Luís; Cardoso, Alisson Assis; http://lattes.cnpq.br/8216536516894987; Vieira, Flávio Henrique Teles; http://lattes.cnpq.br/0920629723928382; Vieira, Flávio Henrique Teles; http://lattes.cnpq.br/0920629723928382; Cardoso, Alisson Assis; http://lattes.cnpq.br/8216536516894987; Vinhal, Cássio Dener Noronha; http://lattes.cnpq.br/9791117638583664; Brito, Leonardo da Cunha; http://lattes.cnpq.br/6660680440182900; Calixto, Wesley Pacheco; http://lattes.cnpq.br/9073478192027867This thesis presents a data classification methodology entitled NL-TSDR (Nonlinear Two-Stage Dimensionality Reduction), aimed at mitigating the challenges posed by high- dimensional datasets and their inherent class masking problems. This phenomenon occurs when overlapping instances from di!erent groups lead to the degradation of traditional classification methods’ performance. The proposed method comprises two distinct stages. In the first stage, the objective is to extract discriminative features by maximizing pairwise class separation probability, e!ectively mitigating class overlap. The second stage applies nonlinear transformations (hyperbolic tangent, Gaussian, sigmoid, and Laplacian functions) to enhance class center separability through multi-objective optimization that maximizes inter-class distances while minimizing intra-class dispersion. Experimental validation was conducted on benchmark datasets and real social media engagement data. The method demonstrates consistent improvements across all evaluated scenarios, achieving superior accuracies even with significant dimensional reduction. Specifically, on the social media dataset, the method achieves a 3.04% accuracy improvement over baseline methods, simultaneously obtaining a dataset that is five and a half times smaller than the original. The analysis of variance (ANOVA) with p = 0.0034, corroborated by paired t-test (p = 0.0199) and Wilcoxon test (p = 0.0153), indicates a statistically significant di!erence (p → 0.05) between the classification accuracies of the original data and the data processed by the proposed method. The results demonstrate that NL-TSDR provides an e!ective tool for addressing class masking in high-dimensional classification tasks while maintaining computational e"ciency suitable for real-world applications.Item type: Item , Para além da dor: a incidência do masoquismo nas elaborações freudianas do aparelho psíquico(Universidade Federal de Goiás, 2025-10-06) Farias, Daniel Berg de Melo; Santos, Altair Jose dos; http://lattes.cnpq.br/2734116381590215; Santos, Altair Jose dos; http://lattes.cnpq.br/2734116381590215; Burgarelli, Cristovao Giovani; http://lattes.cnpq.br/7094012821984177; Sampaio, Eloy San Carlo Maximo; http://lattes.cnpq.br/8054440122552778This study investigates the incidence of masochism in Freud’s elaborations on the psychic apparatus, seeking to answer in which ways masochism contributes to psychic constitution. It traces how Freud, throughout his work, shifts the status of masochism from an initial conception linked to sadism to a central position in psychic life. In the first phase, during the first two decades of psychoanalysis, masochism appears as the passive aspect of the sadistic drive and as something that escapes the logic of the pleasure principle. In this configuration, when pain becomes the drive’s goal, the psychic economy is shaken, since the drive positions the individual as an object of satisfaction, in contradiction with the predominance of the pleasure principle and its regulatory function. The second phase begins with the theoretical turning point 1920, when Freud introduces the notion of the death drive. From then on, masochism comes to be considered prior to sadism, assuming a constitutive and fundamental role in the organization of the psychic apparatus. This reformulation finds its expression in the second topic, in 1923, which broadens the conception of both the psyche and masochism. Therefore, masochism is seen here beyond pain, as a dimension that organizes the subject—a masochistic dimension of life that supports the experience of living. Its drive-related binding, especially after the formulation of the death drive, inscribes it as a part of life capable of repositioning the individual in the face of suffering. The evidence for this conception is present throughout Freud’s writings, which constitute the main theoretical framework of this study. Thus, masochism ceases to be merely a deviation of libidinal economy and becomes a privileged path for understanding how each individual deals with the constitutive demands of their psychic life.