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A representação do duplo em Ópera dos Mortos, de Autran Dourado
(Universidade Federal de Goiás, 2009-04-29) Pinheiro, Roseli da Silva; Canovas, Suzana Yolanda Lenhardt Machado; http://lattes.cnpq.br/9052844036518506; Canovas, Suzana Yolanda Lenhardt Machado; Turchi, Maria Zaira; Carvalho, Maria Luiza Ferreira Laboissiere de
Autran Dourado (1926-2012), a contemporary writer from Minas Gerais, is the author of a whole range of books, such as: novels, short-stories, memorials and articles. In great part of his books, he has recreated the mythical reality of small towns from his home state. The purpose of this dissertation is to study the myth of the double associated to some categories of baroque as a style – in his book Ópera dos mortos (1967). When it comes to the fictional plot, we highlight the narrative clues and the duplication of scenes, the symbolical objects, the double in time and space, as well as the characters in confrontation with their own double. Furthermore, we investigate intratextual and intertextual elements in the novel. When we outline a brief summary of the most important moments in the history of Baroque in the western world, we systematize its main features according to some studies carried out by Helmut Hatzfeld, and, above all, Henrich Wölfflin, and we selected some manifestations of this artistic movement in Brazil, especially in Minas Gerais. By pointing out a historical outline of the myth of the double in the western world, we emphasize the study carried out by Otto Rank, and briefly emphasize the ideas of a contemporary philosopher called Clément Rosset. At last, we analysed the intratextual and intertextual aspects of the novel, mentioning the studies of Mikhail Bakhtin and Julia Kriteva. The double movement, which heads towards modernity without getting away from tradition, is represented in the narrative by a space, known as Gerais, which is, at the same time, an undetermined place where the dead people’s story influences the fate of the living. In our reflexions, we take into account the studies developed by the author himself in his article Uma poética do romance: material de carpintaria (1976), and in the books O meu mestre imaginário (1982) and Breve manual de estilo e romance (2003).
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Estudo comparativo entre a técnica Scuba mofificado e um novo modelo de câmara artificial na manutenção da integridade macroscópica do preparo do complexo endotélio - descemet para o transplante endotelial da córnea
(Universidade Federal de Goiás, 2024-05-14) Moraes Filho, Leiser Franco de; Isaac, David Leonardo Cruvinel; Silva, Leopoldo Magacho dos Santos; http://lattes.cnpq.br/8749557033319190; Silva, Leopoldo Magacho dos Santos; Ávila, Marcos Pereira de; Beniz Neto, Jose; Nassaralla, Belquiz Rodrigues de Amaral; Louzada, Ricardo Noguera
This study is intended to compare the preparation time and the macroscopic integrity of Descemet’s membrane-endothelium complex for endothelial corneal transplantation with DMEK between the modified SCUBA technique and the use of new artificial chamber that works with the inverted cornea. This is a prospective, comparative, randomized and experimental study performed at CEROF-UFG. Fifty corneas from 25 donors were used, including both eyes of the same donor, scleral ring greater than 3 mm, corneas not suitable for clinical use. Preparation time and macroscopic tissue integrity at the end of preparation were evaluated. The median preparation time for both techniques was six minutes (p=0.290). The macroscopic integrity of the graft was similar between the inverted artificial chamber technique and the modified SCUBA technique (p=1.00). Macroscopic integrity was consider as grafts with tears smaller than 2 mm from the edge of the tissue after 8 mm trepanation. The artificial chamber that operates with the inverted cornea proved to be reproducible and suitable for endothelial graft preparation for the DMEK technique.
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Otimização e validação de método bioanalítico para determinação do canabidiol em plasma e obtenção de parâmetros farmacocinéticos em diferentes modelos animais
(Universidade Federal de Goiás, 2024-03-28) Santiago, Nathânia Rodrigues; Cunha, Luiz Carlos da; Graziani, Daniel; Martins, Danieli Brolo; http://lattes.cnpq.br/2159963349521553; Martins, Danieli Brolo; Costa, Renata Mazaro e; Sgobbi, Lívia Flório; Cruz, Alessandro de Carvalho; Salazar, Vania Cristina Rodríguez
It has dozens of substances called phytocannabinoids, including cannabidiol, a non-psychoactive phytocannabinoid with several therapeutic activities described.. In this sense, the objective of this work was to develop a reliable, economical and robust bioanalytical method to evaluate the pharmacokinetic parameters of cannabidiol in plasma of Wistar rats and dogs. The samples were then evaporated and reconstituted in methanol and formic acid and injected into an HPLC system. Separation was performed using an ACE® C18 column (100 mm × 4.0 mm, 5 μm) at 35 ◦C with isocratic elution using an aqueous phase A (10 mM ammonium formate) and an organic phase B (0.1% methanol/formic acid) (10:90 v/v) under a flow rate of 0.6 mL/min and injection volume of 10 μL. This new method showed linearity in the range of 1–5,000 ng/mL and a lower limit of quantification (LLOQ) of 1 ng/mL, which is comparable to the previously reported LC–MS/MS methods. Inter- and intraday precision and accuracy were less than 15% of DSR and DO, respectively. To demonstrate the suitability of the method for in vivo studies in rats, the assay was applied to a preliminary pharmacokinetic study following IV administration of 10 mg/kg CBD and 20 mg/kg orally. Pharmacokinetic analysis revealed the following: t1/2 CBD, 4.56 h (i.v.) and 3.27 h (p.o). The mean absorption time of oral CBD was 0.08 h, indicating that injectable CBD is primarily absorbed within one hour. Clearance (CL) and volume of distribution (Vd) were 4.8 L·h−1 kg−1 and 33.3 L·kg−1. In conclusion, a simple, sensitive, and cost-effective LC/MS-MS method for CBD determination has been developed, validated, and successfully applied to a pharmacokinetic study in rats.
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Contribuições da prática de yoga na percepção dos sintomas de estresse, ansiedade e depressão em estudantes universitários
(Universidade Federal de Goiás, 2025-03-11) Lemes, Uitairany do Prado; Borges, Cezimar Correia; http://lattes.cnpq.br/3658236531711777; Chaveiro, Neuma; http://lattes.cnpq.br/1345257253831999; Chaveiro, Neuma; Guimarães, Valeriana de Castro; Paiva, Rosane Emanuele
Introduction: University students are particularly susceptible to increased stress, anxiety, and depression, especially medical students. Yoga, a non-pharmacological alternative, has gained legitimacy due to its inclusion in Integrative and Complementary Practices, ease of application in Higher Education Institutions, and evidence on mental health parameters. This dissertation investigated the effects of yoga on the mental health of university students through a systematic review protocol, a systematic review, an integrative review, and an experimental study. The central objective was to determine if a yoga program could reduce stress, anxiety, and depression, and improve self-reported quality of life. The research was structured into four articles, each addressing a specific aspect of yoga's effects in the academic context. Products: The systematic review analyzed 12 experimental studies with 1,660 participants. Yoga showed significant effects, most notably in reducing stress, followed by anxiety, and to a lesser extent, depression. Hatha Yoga was the most studied modality, with interventions lasting 6 to 12 weeks. Methodological quality was assessed using Cochrane tools: five studies had low risk of bias, six had moderate risk due to randomization and blinding issues, and one had high risk. The integrative review focused on stress, synthesizing 10 articles that showed yoga effectively reduces perceived stress, with moderate to small effects. Combining physical practices, breathing exercises, and meditation was particularly effective. Hatha Yoga was the most frequent modality. The review highlighted the need for more research on the optimal intensity and proportion of movements and meditation. The experimental study involved 48 medical students in two groups: Yoga Group (GY) and Meditation Counseling Group (GAM). Over 8 weeks, pre- and post-intervention assessments measured stress, anxiety, depression, and quality of life. In GY, anxiety scores (GAD-7) dropped from 13.4 ± 4.7 to 5.8 ± 4.4 (p < 0.001), indicating a large effect; in GAM, from 13.2 ± 5.0 to 8.8 ± 5.1 (p = 0.010). For stress (EPS10), GY scores fell from 27.5 ± 4.6 to 19.4 ± 2.4 (p < 0.001), a large effect; GAM scores decreased from 26.4 ± 6.4 to 20.2 ± 6.8 (p < 0.001). Depression (DASS-21) showed small to moderate effects in GY and moderate to large in GAM. Quality of life (SF-12) improved slightly in GY (p = 0.075 for physical health; p = 0.270 for mental health), without statistical significance. Conclusions: Yoga is an effective intervention for reducing stress, anxiety, and, to a lesser extent, depression among university students, especially in medical school. Implementing regular yoga programs in universities can promote a healthier academic environment. Future research should explore longer interventions and various yoga modalities to enhance these benefits further
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Contra os tigres de papel: juventude, cinema e resistência ao regime militar em Goiás no filme "A Fraude" (1968)
(Universidade Federal de Goiás, 2025-02-12) Estevão, Lara Damiane de Oliveira; Teixeira , Rafael Saddi; http://lattes.cnpq.br/2919949012379731; Teixeira , Rafael Saddi; Abdala Júnior, Roberto; Oliveira, Alcilene Cavalcante de; Cardoso, Maria Abadia; Távora, Adérito Schneider Alencar e
In 1968, a group composed mainly of young students filmed the short movie A Fraude in Goiânia to compete in the IV Amateur Film Festival organized by Jornal do Brasil, an important platform for showcasing films in the second half of the 1960s. Directed by Jocelan Melquíades de Jesus, the film portrays Luiz, a student who became an excedente – those who achieved a sufficient score in the university entrance exam but was not admitted due to a lack of available spots – during the admissions process for the Faculty of Medicine at the Federal University of Goiás (UFG) in 1968. During the military dictatorship, resistance through cultural action was also reflected in the activities of intellectuals and artists in Goiás. This study analyzes the production process of A Fraude and employs film analysis to understand how youth appropriated cinema as a form of resistance against the Brazilian military dictatorship. That year, prospective students took to the streets of the state capital, Goiânia, alleging that the UFG administration itself had perpetrated fraud in the admissions process. Through the film's imagery, the creators captured the specificities of the conflicts between the military regime, universities, and students in Goiás, addressing the theme of underdevelopment and denouncing the government’s subservience to U.S. imperialism, as expressed through the MEC-Usaid agreements. In alignment with the aesthetic and narrative tendencies of Brazilian modern cinema, a group of students filmed reality to confront it, constructing a perspective on Goiânia, the student revolt, and the military dictatorship through the use of allegory, with a tone that oscillates between didacticism and exasperation.