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Item Estudo clínico e epidemiológico das apresentações iniciais de pacientes com transtorno afetivo bipolar–tipo I e II(Universidade Federal de Goiás, 2013-09-30) Chaves, Moysés de Paula Rodrigues; Caixeta, Leonardo Ferreira; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4735432Y9There are several studies on the differential diagnosis of Bipolar Disorder (BD), however, further investigation with an emphasis on clinical phenotypes that inaugurate the disease is needed. The aims of this study are to identify the psychiatric disorders most frequently diagnosed before the definitive diagnosis of BD, the time until the correct diagnosis and compare BD I and II for the variables studied. We studied 259 patients with current diagnosis of BD according to the DSM- IV-TR, evaluated by the same psychiatrist. Early psychiatric signs and symptoms were identified through an interview with the patient and family members and were considered suggestive of an initial diagnosis that was coded according to the same diagnostic criteria. The authors analyzed data on patients' age at prodromes suggestive of initial psychiatric diagnosis and time delay to the actual diagnosis of BD. Comparisons were made between sex, schooling and type of BD. The mean age of patients was 41.6 years, with a predominance of adults (19-60 years), women (67.6%), as well as type II BD (68.3%). Patients were on average 24.6 years of age at initial diagnosis, 41.6 years in the diagnosis of BD and the mean time delay between these was 16.9 years. The most common initial diagnoses were depressive disorders (41.3%), anxiety (12.7%), ADHD (8.1%), disorders related to substance abuse (7.7%), somatoform disorders (6 9%), and psychosis (5.4%). BD can be considered a “great imitator” in modern psychiatry, since initial phenotypes can mimic other disorders. BD diagnosis is very delayed in Brazil.Item A graduação médica e a prática profissional na perspectiva de discentes do internato de medicina(Universidade Federal de Goiás, 2013-08-30) Filisbino, Marcos Augusto; Moraes, Vardeli Alves de; http://lattes.cnpq.br/2078225868415338This research was conducted in medical school of Federal University of Goiás. OBJECTIVES: The aim of this research is to identify the ideal, in terms of professional practice, of the internship students in the Medical School of the Federal University of Goiás – UFG − and to observe possible dissonances with the profile of the graduates, as advocated by the National Curriculum Guidelines and by the Political Pedagogic Project of this institution. METHODS: In 2012, two hundred and twenty-two medical internship students of the institution received a survey questionnaire. The sample of this research consisted of one hundred and ninety research subjects, representing 85% of the sample universe. The statistical significance was calculated using a non-parametric test (Sign Test). RESULTS: The sociodemographic profile characterizes the students with an average age of 23,8 years old, unmarried, 65,8% of whom belong to social classes A and B. The ideal of the profile of professional practice shows that 83,7% want to become specialists, whereas 96,3% want medical residency, which is statistically significant (p=0,0001), and 71,6% do not intend to work with Family Health Strategy Programs (p=0,005). CONCLUSION: This study shows that students with high socio-economic profile, who want to become specialists, undergo a medical residency program and do not see the Family Health Strategy as a professional goal.Item Efeito do nicotinato de cromo na sensibilidade à insulina e antropometria em indivíduos com diabetes mellitus tipo 2(Universidade Federal de Goiás, 2012-02-02) Guimarães, Marília Mendonça; Silva, Maria Sebastiana; http://lattes.cnpq.br/1329422634395496Chromium dietary interventions have been used to investigate the improvement in insulin sensitivity due to the role of chromium as a central component of the glucose tolerance factor. This study aims investigate the effect of chromium nicotinate supplementation on insulin sensitivity and anthropometry in type 2 diabetic subjects. In double-blind trial, fifty-six type 2 diabetic subjects with Body Mass Index 25 kg/m2 and increased waist circumference were randomized into three groups: placebo (NC0), 50μg (NC50) and 200μg (NC200) of chromium nicotinate. Status of chromium, insulin resistance, cell function, glycemic control, lipid profile, anthropometry, intensity and energy expenditure in physical activity were assessed at the beginning, 45 and 90 days of intervention. Energy consumption was assessed at the beginning, between the beginning and 45 days and between 45 and 90 days of study. Most subjects had low serum levels of chromium (71.88%), normal levels of urinary chromium (80.65%) and insulin resistance (73.80%). Chromium serum concentrations did not differ between groups over time (p = 0.2549). Changes in concentrations of serum and urinary chromium were not related to changes in fasting glucose (p> 0.05). At 90 days, there was no significant intra-group difference in fasting plasma glucose, glycosylated hemoglobin, HOMA-IR, total cholesterol, LDL cholesterol, waist circumference, % body fat and % lean mass. There was an increase in HOMA- (p = 0.0349) and HDL cholesterol (p = 0.0425) in the group NC0, reduction in triglycerides in NC0 group (p = 0.0177) and NC50 (p = 0.0336) and reduced of 1.08 kg in the NC50 group (p = 0.0048). No difference was found at intra-group physical activity intensity and between supplemented groups (NC50 and NC200) and placebo (NC0) at 90 days (p>0.05). There was an increase in physical activity energy expenditure in NC50 group at 90 days (p = 0.0371). As for total energy intake, there was no difference within and between groups during the study (p> 0.05). Supplementation with 50 μg and 200 μg chromium nicotinate for 90 days did not promote improvements in glucose homeostasis, lipid profile and anthropometry in individuals with type 2 diabetes mellitus.Item Análise epidemiológica dos cânceres de pulmão e da laringe em 30 anos(Universidade Federal de Goiás, 2014-06-26) Martins, Edesio; Oliveira, José Carlos de; Curado, Maria Paula; http://lattes.cnpq.br/3397823736381748; Curado, Maria Paula; Campoli, Paulo Moacir de Oliveira; Rabahi, Marcelo Fouad; Freitas, Nilceana Maya Aires; Paula, Adriano Augusto Peclat deIntroduction: Studies have shown a relationship between smoking and various cancers, especially in the respiratory tract, causing major impact on public health. Lung cancer is the leading cause of cancer death in the world, accounting for 20 %, while Laryngeal cancer represents 3 %. Objective: To analyze trends in incidence and mortality from lung and larynx cancer in Goiania in 20 years and to assess trends in mortality for these cancers, over the past 30 years for the Brazilian regions. Methods: All incident cases of lung cancer and larynx were obtained from the database registered in Goiania RCBP/ACCG and deaths were extracted from the Mortality Information System (SIM/MS) for both, Goiania as for other Brazilian regions. Incidence rates and standardized mortality rates were calculated using the world standard population and calculating the trend used the Poisson regression model using Joinpoint Regression Program, Version 4.0.4. Graphs and tables were made using the Excel 2013 software. Results: Two points were analyzed: the first showed that the trend of incidence for lung and larynx cancers in both sexes and age groups in Goiania, were in contrast to trend mortality for lung cancer in women over 50 increased by 2.5% per year, during the study period in Goiania. The second article assessed the trends in national mortality for cancers of the lung and larynx showing that in Brazil, the mortality rates for lung cancer ranged from 14.30 to 15.52/100,000 in men and 3.99 to 7.37/100,000 in women from 1980 to 2009. Laryngeal cancer in this variation was from 3.76 to 3.59/100,000 for males and 0.47 to 0.38/100,000 in the female. The analysis of trends showed increased mortality for lung cancer in both male and female genders respectively (APC 1.7 %; 95% CI 1.6 to 1.8, p < 0.001, and APC 4.1%; 95% CI 3.9, the 4.2, p < 0.000). Mortality rates for laryngeal cancer in men the increase was 1.4 % (95% CI 1.2 to 1.5 p < 0.0001), the rate for women increased by 1.3 % (95 % 0.9 -1.6, p < 0.0001) during the study period, so there were similar for both neoplasms. Conclusion: Incidence trends were stable for lung and larynx cancer in both sexes and age groups, in contrast, for women aged over 50 years there has been increasing trends in mortality in Goiania. When Abstract xviii analyzing mortality at the national level, there was decline for lung cancer in south and southeast whereas for cancer of the larynx, there was a decrease only in southeastern Brazil.Item Avaliação da composição corporal de mulheres recém-diagnosticadas com câncer de mama(Universidade Federal de Goiás, 2010-01-19) Martins, Karine Anusca; Monego, Estelamaris Tronco; http://lattes.cnpq.br/0917323812776538; Freitas Júnior, Ruffo de; http://lattes.cnpq.br/7343840830786566Introduction: Body composition modification, mainly the increase in total body fat, which is related to a number of illnesses, is an important public health problem, is quite prevalent in breast cancer patents and is directly associated with a negative prognosis for the illness. Objective: To evaluate the body composition, of total body fat and its distribution and lipid profile of women recently diagnosed with breast cancer, at two referral centers in Goiânia, Goiás. Methodology: (Article 1) A cross-sectional, cohort nested study. (Article 2). A case-control study, with 1:1 pairing, carried out in Goiânia, Goiás, Brazil. The data were collected through interviews based on questionnaire, with 62 women, a socio-demographic characterization and an evaluation of body composition using anthropometry including skinfolds (SF) and circumferences, bioelectrical impedance analysis (BIA) and ultrasonography (USG), besides the evaluation of lipid profile. Were carried an data tabulation (Excel/2003) and analysis (SPSS program, version 8.0) and (STATA, Intercooled Stata 8) and were used descriptive statistics. Was used in the data analyses: the Kolmogorov-Smirnov test, ??t?? test, chi-square for tendency, (Mann-Whitney U), Pearson??s chi-square, Fisher??s exact test, and Yates?? correction, odds ratio, Pearson??s correlation coefficient (r), concordance correlation coefficient (CCC) and determination index (r2). The level of significance was: p < 0.05. Results: Compared with the controls, women with breast cancer (cases) had lower stature (1.56m±5.68) and (1.59m±6.92); greater body fat as measured by bioelectrical impedance (BIA) (39.87% ±8.26) and (36.00%±6.85) and (63.98%±6.87); and larger tricipital skinfolds (27.55mm±8.37) and (22.81mm±5.72), respectively. Seventeen (54.84%) cases and 19 (61.29%) controls presented increased abdominal adiposity and 20 (64.52%) of cases and 22 (70.97%) of controls were overweight (BMI ? 25.0 Kg/m2). A moderate concordance (CCC=0.59; r2=0.42; p<0.01) was identified between the methods (BIA and sum of skinfolds - ?SF) for determining body fat (%) and optimal concordance (r2=0.90; CCC=0.91; p<0.01) for body fat (Kg). The comparison between the methods of evaluation body fat distribuition (Waist Circumference (WC) and intra-abdominal thickness (IAT) for (USG) evidenced a moderate concordance (r2=0.49; p<0.01), between the methods. No association was found between the lipid profile and breast cancer occurrence. Conclusions: Women with breast cancer presented lower stature, a greater percentage of body fat and and larger tricipital skinfolds than women without cancer. A moderate concordance, between the methods used in determining total body fat (%) and a optimal concordance in determining body fat (Kg) were found. A moderate concordance were found between the methods in determining body fat distribution (IAT x WC).Item Análise fotoelástica da distribuição de tensões peri-implantares em overdenture mandibular retida por implante unitário com diferentes tipos de conexão(Universidade Federal de Goiás, 2013-08-14) Nascimento, João Francisco Machado do; Leles, Cláudio Rodrigues; http://lattes.cnpq.br/6740286066154410For patients poorly adapted to conventional dentures, the single-implant mandibular overdenture has been proposed as a simplified alternative for the two-implant treatment, together with the use of immediate loading of the implant. The aim of this in vitro study was to compare the photoelastic characteristics of stress transfer to the implant in a single-implant mandibular overdenture using different types of attachments. A photoelastic model of an edentulous mandible with a resilient edentulous ridge and a unique implant located at the symphyseal region was obtained to reproduce a single implant-retained mandibular overdenture. Six 2.0 mm height attachments were selected and inserted in the same photoelastic model in a random order. A universal material testing machine was used to induce axial vertical loads of 70 N applied in the central incisor and in the central region of the first right molar without contact on the contralateral side. The photoelastic analysis was performed using a polariscope integrated into the testing machine. Standard separate views were photographed and evaluated visually for stress-induced fringes, to comparatively rank the different attachment systems. All attachments showed a similar tension distribution concentrated in the apical third, and the highest stress concentration at the apical level. There was a low stress concentration at the coronal third of the implant, with no discernible stress in the first threads of the implants, except for Dalla Bona which showed low stress at the coronal part of the implant (one fringe). No identifiable fringes were observed when the load was applied in the molar region, which resulted from the low amount of stress transmitted by the implant for all attachments. It was concluded that the load transferred to a single mandibular implant is low and within the limits of functional loading, irrespective of the type of retention system.Item Prevalência da Doença Pulmonar Obstrutiva Crônica e de seu subdiagnóstico em pacientes hipertensos do Programa HIPERDIA de uma unidade de atenção primária à saúde na cidade de Goiânia(Universidade Federal de Goiás, 2013-05-06) Pereira, Sheila Alves; Rabahi, Marcelo Fouad; http://lattes.cnpq.br/1489771770609266Introduction: The detection of patients with Chronic Obstructive Pulmonary Disease (COPD) on the primary health care network can be an important tool for an early diagnosis and better conduct management of these patients. Studies realized in Latin America (MENEZES, 2006) show that the COPD underdiagnosis is one of the great limiters for the control of this illness. It was also observed in a study in Canada (Hill et al., 2010) that half of the cases sub-diagnosed were of hypertensive patients. Thus, the analysis of the pulmonary function in hypertensive patients could be a useful strategy for the diagnosis of patients with COPD. Objective: To estimate the prevalence of COPD and its sub-diagnosis on hypertensive patients registered on the HIPERDIA Program of an unit of primary health care in Goiânia. Methodology: The transversal analytical study performed on the Novo Horizonte CIAMS in Goiânia from January/2011 to May/2012, with patients from both sex, aged between 18 and 80 years old and hypertensive registered on the HIPERDIA Program. The patients were evaluated as for the pulmonary function (spirometry) and the respiratory symptoms (questionnaire). The criteria used for the diagnosis f COPD were in fixed relation of the VEF1/CVT<0,70 or by the relation VEF1/CVF below the inferior limit of normality. For the statistical analysis, it was appealed to the SPSS 17.0 program, with the execution of the square Qui test, T test and analysis of the logistical regression. The level of statistic significance assumed was of p < 0,05. The present study was approved by the Ethical Committee of Human Research from the Clinical Hospital of the Federal University of Goiás, register n° 159/2010. Results: 301 patients were evaluated. The prevalence of COPD was of 22,2% and the sub-diagnosis rate was of 82%. The group with normal spirometry (n=165) was compared to the group with COPD (n=67) as for the social demographic variables, pulmonary function, risk factors, the respiratory symptoms and the co morbidity. There were significant differences only in relation to the sex (p<0,001), age (p=0,005), CVF, VEF1/CVF (p<0,001), smoking (p<0,001) and wheezing (p=0,006). The group of patients with sub-diagnosed with COPD (n=55) and with previous diagnosis (n=12) were similar as for all the variables of epidemiological characterization, except for the respiratory symptoms (wheezing and dyspnea) and pulmonary function. Conclusion: The COPD patients’ profile is similar to the literature. The high prevalence of COPD found in the patients on the HIPERDIA Program with the majority of the sub-diagnosed, shows that the implantation of management strategies with patients with COPD in this National Program of Public Health is already existent in the majority of the Brazilian cities.Item Efeitos do treinamento aeróbio e resistido sobre a qualidade de vida e capacidade funcional em mulheres hipertensas(Universidade Federal de Goiás, 2010-05-05) Póvoa, Thaís Inacio Rolim; Sousa, Ana Luiza Lima; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4728701H7; Jardim, Paulo César Brandão Veiga; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4781358P2; Salgado, Cláudia Maria; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4736530A6; Silva, Maria Sebastiana; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4791881D6; Zanni, Cláudia Regina de Olinveira; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4706955U7; Barbosa, Maria AlvesINTRODUCTION: Hypertension could impaire the quality of life (QOL) and healthrelated quality of life (HRQOL). Aerobic and resistance training improve cardiovascular performance, but there is little evidence regarding the effects related to QOL, HRQOL and functional capacity in hypertensive women. OBJECTIVES: To assess the effects of aerobic and resistance training on QOL and functional capacity in hypertensive women. METHODS: Randomized clinical trial conducted at Hypertension League Federal University of Goias - Brazil. Sample: hypertensive women, 50 years, non-participants in exercise programs, satisfactory treadmill test (Bruce protocol) and with a minimum 6- month treatment at service. Subdivided: aerobic group (GA) (n=21) and resistance group (GR) (n=20). Interventions: 2 months (2x/week) of aerobic exercise and resistance training. Intensity of aerobic group: light to moderate (4 to 7 of adjusted Borg Scale). Resistance: up to 60% of 1 RM Test. Two series of 12 to 15 repetitions. Before and after the intervention was applied WHOQOL-bref to evaluate QOL, the SF-36 for HRQOL and 6-minute walk test (6`WT) to measure the functional capacity. Statistical: student`s-t, Fisher, Mann-Whitney U, Chi-square and Wilcoxon tests. Level of significance: p <0.05. RESULTS: Initially the groups were homogeneous regarding clinical, anthropometric, sociodemographic and WT6’ (p 0.05). The groups were also homogeneous in WHOQOL-bref scores except on the psychological and social relationships domains, and the GR had higher scores on these. On SF-36, the groups were different at the beginning only at physical function domain, and the GA presented higher score in this domain. After intervention, there was a significant improvement in all WHOQOL-bref domains in GA and at GR the improvement ocurred only in physical health domain. Regarding SF-36 there was a significant improvement in 7 of 8 domains at GA (exception for mental health). At GR, were observed similar results. There were no changes in weight, body mass index, waist circunference, blood pressure and heart rate after the intervention. (p 0.05). There was an increase at functional capacity (longer distance on 6`WT - p 0.001) in both groups. CONCLUSION: The two types of physical exercise, promoted beneficial effects in different magnitudes in QOL, similar in HRQOL and functional capacity. These results suggest that, according the focus and objectives established, both exercises can be effective as a treatment strategy in search of better QOL in hypertensive woman.Item Estresse parental em mães de bebês, crianças e adolescentes com paralisia cerebral(Universidade Federal de Goiás, 2013-03-19) Ribeiro, Maysa Ferreira Martins; Vandenberghe, Luc; http://lattes.cnpq.br/5143352856295345; Porto, Celmo Celeno; http://lattes.cnpq.br/9673684282497548This thesis follows the scientific article model. The first article, “Parental stress in families of children with cerebral palsy: an integrative review”, was submitted and accepted for publication in the journal Ciência & Saúde Coletiva. Objectives: to select, evaluate and interpret critically the bibliographic production focused on the stress experienced by parents/caregivers of children with cerebral palsy. Methods: an integrative literature review. Sources for this search were the Virtual Health Library (VHL), the United States National Library of Medicine (PubMed) and manual search of references from the selected studies. We opted to select studies published between 1998 and 2011. Results: the sample included 13 articles. Parents of children with cerebral palsy have higher stress levels than parents of children without disabilities. Behavioral problems, psychological disorders and emotional needs of children were factors commonly associated with high levels of stress. Satisfaction with social support, self-satisfaction with the parental role, a good family functioning, an emotional bond between father/mother and child, the spousal support and the sense of being an active participation in social life help reduce stress levels. The second article, “Parental stress in mothers of babies, children and adolescents with cerebral palsy”, will be submitted to Revista Latino-Americana de Enfermagem. Objectives: a) evaluate the parental stress in mothers with cerebral palsy; b) to verify variations in parental stress among mothers of children with mild motor impairment (levels I/II on the Gross Motor Function Classification System - GMFCS) and severe motor impairment (GMFCS levels IV/V); c) to evaluate the parental stress level in mothers whose children are classified at levels I, II, IV and V on the GMFCS and check the influence of motor impairment on the maternal stress; d) assess variations in parental stress among mothers of adolescents with cerebral palsy classified at levels I / II and IV / V of the GMFCS; e) to check if the parenting stress varies according each stage of child’s: infancy, childhood and adolescence; f) to relate the parental stress with socio-demographic variables: mother age, education, family income, profession/job, marital status, number of children, kind of transportation, participation in leisure activities and psychological support. Methods: analytical cross-sectional study with 223 mothers of babies, children and adolescents with cerebral palsy. The parenting stress was measured by the Parenting Stress Index Short Form (PSI / SF), that consists of 36 items which comprise three subscales. Método: Cross-sectional, descriptive study with 223 mothers of babies, children and adolescents with cerebral palsy. The parenting stress was measured by the Parenting Stress Index Short Form (PSI/SF), that consists of 36 items which comprise three subscales. Results: a) 45.3% of the mothers had high level of parental stress; b) mothers of children at GMFCS Levels I/II had higher stress level on the subscale "difficult child" whose issues are related to children’s behavior; c) among mothers of children at GMFCS Level V the stress was high for all the questionnaire, revealing that it comes from a broad context that includes mothers’ and children’s characteristics and how they cope with the demands; d) mothers of adolescents in levels I / II were more stressed than mothers of adolescents in levels IV / V; e) levels of parental stress vary according to children development stage; mothers of children were more stressed than mothers of babies and adolescents; f) paid work and leisure contribute to stress reduction. Conclusion: mothers of infants, children and adolescents with cerebral palsy, whose sons have motor impairment, from mild to severe, are vulnerable to parental stress. Paid work and leisure activities were the factors that contributed most to reduce stress.Item Avaliação do programa de rastreamento mamográfico oportunístico realizado pelo Sistema Único de Saúde, no município de Goiânia, em 2010: desempenho dos centros de diagnóstico e indicadores para monitoramento de resultados(Universidade Federal de Goiás, 2012-06-27) Rodrigues, Danielle Cristina Netto; Rahal, Rosemar Macedo Sousa; http://lattes.cnpq.br/1322145394447454; Freitas Júnior, Ruffo de; http://lattes.cnpq.br/7343840830786566Introduction: Among governmental measures in support of strategies to control and prevent breast cancer in Brazil, the implementation of the Breast Cancer Control Information System (SISMAMA) has made it possible for Single Health System (SUS) managers to identify users and diagnostic centers and provide data to the National Mammmogram Quality Program (PNQM) as a way of guaranteeing adequate tracking and establishing indicators for monitoring mammography results in each region of the country. Objective: To evaluate the opportunistic mammographic screening program carried out by the Single Health System in the municipality of Goiânia en 2010 in regard to the performance of diagnostic centers and indicators for monitoring results. Method: This was an ecological study in which the results of mammograms performed by SUS on the female population of Goiânia from January to December, 2010 and reported by diagnostic centers to SISMAMA were analyzed. The data were collected from the “export data” file of the state coordination module and the variables studied were analyzed in the two articles produced on the basis of this study. In Article 1, the variables studied were test production by diagnostic center, monthly test volume, tests by clinical indication, screening tests by age group and screening tests by diagnostic conclusion using BIRADS® categories (0,1,2,3,4 and 5). To evaluate the conformity of the diagnostic centers, an arbitrary variation limit of ± 30% of the relative frequency of all diagnostic centers in each BIRADS® category was established. Those centers found to be within this limit were considered to be in conformity. Centers with the same conformity percentage were considered to have the same performance. For Article 2 the variables were mammography distribution by age group, diagnostic conclusion, earlier mammograms and those indicated for biopsy. The following indicators for monitoring the results for the 50- 69 year age group were calculated: participation (coverage) rate, test rate by BIRADS® category (1,2,3,4 and 5), recall rate (BIRADS® 0), percentage of positive mammograms (BIRADS® 0, 4 and 5) and the biopsy indication rate (BIRADS® 4 and 5). Results: In Artlcle 1, of the 31,454 tests carried out on women residing in Goiânia, 8,268 (26.3%) were reported by the proprietary SUS diagnostic center network and 23,186 by the accredited network. Test distribution by age group and type of network shows that 43.3% of tests were carried out on women in the 40-49 year age bracket and 44.8% on women from 50 to 69 years old. Diagnostic conclusion performance was uneven among the diagnostic centers for BIRADS® categories 1,2,3,4 and 5 as well as for BIRADS® category 0 in comparison with the other categories, with p<0.001. In Article 2, for the 50-69 year age bracket, the biennial screening coverage estimate was 25.2% and the mammography ratio for 2010 was 0.14. The indicators for monitoring the results of the SUS opportunistic mammography screening program were the following: the recall rate was 9.6% (BIRADS® 0) and the normal test rate (BIRADS® 1 and 2) was 86.1% while the percentage of positive mammograms (BIRADS® 0, 4 and 5) was 10.9% and the biopsy indication rate was 1.3% (BIRADS® 4 and 5). Conclusion: An analysis of the results makes it possible to construct the first opportunistic mammography screening indicators for Goiânia. These will serve as parameters for monitoring early breast cancer detection measures. MMG services’ unequal diagnostic conclusion performance points to the necessity of implementing result auditing in screening programs to monitor the quality of mammographic test interpretation.Item Efeitos clínicos, laboratoriais e ecocardiográficos da estimulação cardíaca convencional em pacientes submetidos a implante de marca-passo com função ventricular normal(Universidade Federal de Goiás, 2013-02-22) Sá, Luiz Antônio Batista de; Rassi, Salvador; http://lattes.cnpq.br/7236834842677715; Freitas Jr, Aguinaldo Figueiredo de; Brasil, Luiz Antônio; Medeiros, Paulo de Tarso Jorge; Souza, Weimar Kunz Sebba Barroso de; Rassi, SalvadorIntroduction: Right ventricular pacing can be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation and triggering ventricular dyssynchrony clinically relevant is not fully established. Objectives: To evaluate clinical findings of patients with previously normal ventricular function, who underwent implantation of a pacemaker. Methods: We studied prospectively 20 patients (60% male and the average age was 58 years) underwent implantation of a pacemaker with the following inclusion criteria: normal ventricular function defined by echocardiography and the presence of ventricular pacing 90% higher (generator telemetry). We evaluated the following parameters: Class functional (New York Heart Association) 6-minute walk test, dosage of B-type natriuretic peptide (BNP), and conventional echocardiographic and evaluation dyssynchrony and intraventricular (by tissue Doppler, M-mode and pulsed Doppler) and the quality of life assessment by SF-36 Health Survey. The evaluation was done at 10 days (t1), 4 months (t2), 8 months (t3), 12 months (t4) and 24 months (t5). Data were compared over time according to ANOVA repeated measures (rmANOVA). Results: Of the following evaluated data showed no statistically significant variation (p> 0.05): conventional echocardiographic parameters, interventricular and intraventricular dyssynchrony. The six minute walk test, functional class and BNP worsened at the end of two years (p <0.05). Evaluation showed initial improvement in QOL domains: physical functioning, social and general health and worsens at the end of the two years. Conclusion: After 24 months the right ventricular pacing, in patients with normal function, correlated with worsening of ventricular function assessed clinically (class functional walk test and QOL) and measure laboratory (BNP).Item Biossegurança - conhecimento de graduandos em farmácia(Universidade Federal de Goiás, 2014-02-28) Salha, Leila Abou; Mendonça, Reginaldo Teixeira; http://lattes.cnpq.br/4683119891747033; Mendonça, Reginaldo Teixeira; Martins, Cleusa Alves; Feres, Valéria Christina de Rezende; Costa, Nilce Maria da Silva Campos; Martins, Karine AnuscaProfessional practice is also guided by the teaching- learning and knowledge in biosafety training of pharmacists , is of paramount importance for the safe and conscientious professional practice . The study aims to investigate the knowledge of undergraduate students about concepts of biosafety aspects in the use of personal protective equipment , standard precautions and immunization . A questionnaire was applied to interview students of pharmacy of a public institution to collect data on biosafety , during the period November 2012 to May 2013. Among the 300 participants , 132 ( 64.4 %) use lab coat and glove 240 ( 80 % ) have knowledge of waste disposal , 246 ( 82 % ) know about measures to protect the safety and health of workers in health services , 289 ( 96 % ) know the correct handwashing and 71 ( 26 % ) reported knowledge of occupational immunization. It was observed that approximately 65 % of the students showed biosafety knowledge and this knowledge did not show the expected periods over the course of the addition. There is need for changes in teaching strategies to be effective in practice biosecurity as essential to professional practice safely content, reaffirming content as transversal and interdisciplinary .Item Efeitos do laser na cicatrização de cesárea em pacientes com diabetes gestacional(Universidade Federal de Goiás, 2013-12-18) Santos, Hugo Campos Oliveira; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579Caesarean section is a surgical technique utilized to deliver the fetus from the uterus and an increase in this surgical procedure can be noted around the world. In Brazil, approximately 40% of total deliveries occur in this way, it is estimated that caesarean section corresponds to 80% of deliveries in private assistance between 2008 and 2012. Diabetes complicates gestation and pregnancy complicates diabetes, this combination increases the possibility of flawed scarring process, which may cause esthetic, psychological and clinical problems. The Low-Level Laser Therapy (LLLT) is an ally for the treatment of a number of wounds – accelerating cell metabolism and reducing inflammatory and infectious processes. The objective of this study was to evaluate the effects of AlGaInP LASER (660nm) treatment regarding wound healing quality and hypertrophic scar prevention in patients with gestational diabetes undergone caesarean section. The clinical study was performed at Hospital das Clínicas of the Federal University of Goiás, after Ethics Committee approval (CEP/HC.053/11). In the period between November (2011) and May (2013) 90 patients divided into 3 groups were assessed: Group A: LASER (3 Joules/cm2), Group B: LASER (6 Joules/cm2) and Group C (Control – no treatment). Caesarean incision was photographed in the periods: T1 (1day), T2 (2days), T3 (3days), T4 (15days) and T5 (30days). Photos were used in order to calculate mean area and standard deviation. The area of the photographs was analyzed and calculated in pixels with specific software (Software Image J – NIH/USA), measuring, thus, the wound contraction in percentage (%). The calculation was performed by the caesarean scar area reduction and the increase of incision contraction percentage (recovery) throughout the periods for each group. Contraction results (%) with regard to wound area were significant (p<0.05) for all groups studied, according to Kruskal Wallis’, Mann-Whitney’s and Wilcoxon’s tests. Groups treated with LASER (A and B) presented higher edge contraction, being 89% the scar reduction of Group A (p<0.001) and 81% of Group B (p<0.05), when compared to control group (73%). However, Group A demonstrated higher wounded area reduction when compared to group B, especially in the period between the 3rd and the 15th day from the postoperative (p<0.001). It was verified that the better performance of Low-power LASER (AlGaInP) occurred in the time reported in the literature as scarring process inflammatory stage (≤7days). Inflammatory process reduction may have contributed to reducing scarring time, increasing wound contraction percentage, benefitting, thus, the incision esthetic aspect throughout 30 days of treatment. During the study, occurrence of hypertrophic scars was not observed in any of the experimental groups in the period of 60days from the postoperative.Item Traumatismos bucomaxilofaciais em um hospital público do Brasil Central: estudo retrospectivo(Universidade Federal de Goiás, 2013-12-10) Scartezini, Guilherme Romano; Alencar, Ana Helena G. de; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Alencar, Ana Helena G. de; Pécora, Jesus Djalma; Sousa, Hugo Alexandre de; Decurcio, Daniel de AlmeidaAim: To evaluate epidemiological aspects of maxillofacial-oral injuries in hospitalized patients. Material and Methods: The sample was composed by 405 patients treated at the Department of Oral and Maxillofacial Surgery of the Emergency Hospital of Aparecida de Goiânia, Brazil, between 2011 and 2013. The following informations were collected from the patients’ medical records: gender, age, cause of injury, seasonal distribution, patient’s location and type of injury. The statistical treatment analyzed data from frequency distribution and chi-squared test. The level of significance was set at 5% for all analyses. Results: Higher occurrence of maxillofacial-oral injuries was observed in males (n=294; 72.59%), with 21-30 years old (n=106; 26.17%) and from the city of Aparecida de Goiânia. The main etiologic factors involved were vehicle traffic accidents (n=124; 30.62%), falls (n=92; 22.72%) and violence (n=87; 21.48%). The seasonal distribution showed that most cases occurred in autumn (n=154; 38.02%), followed by summer (n=138; 34.07%). The most common injuries were facial fractures (n = 324; 80.0%), the nasal bone, the most affected (n = 161; 39.75%) anatomical region. Statistically significant associations between etiological factor, gender and age (p <0.005) were observed. Conclusions: There were a high number of maxillofacial-oral injuries in males, aged less than 30 years old and due vehicle traffic accidents.Item Perfil epidemiológico e associação clínico-radiológica dos pacientes com megaesôfago chagásico acompanhados no Hospital das Clínicas da UFG, no período de 1998 a 2010(Universidade Federal de Goiás, 2013-03-26) SOUZA, Diogo Henrique Saliba de; Rezende Filho, Joffre; http://lattes.cnpq.br/4676204316384198; Oliveira, Ênio Chaves de; http://lattes.cnpq.br/7046861881778720Introduction: Chagasic megaesophagus (CM) is the most common digestive manifestation of Chagas’ Disease (CD) in Brazil and the State of Goiás is one of the most affected regions. The Hospital das Clínicas (HC)/ Universidade Federal de Goiás (UFG) is a reference center for study and treatment of CM in the last decades. The objective of this study was to characterize the current epidemiological profile of patients with CM seen at the HC of the UFG, from 1998 to 2010. Methodology: Nine hundred thirty-nine patients' records were analyzed and age, gender, place of birth, serology, symptoms and radiological classification according to Rezende et al. were analyzed. Results: The median age of patients was 55 years old. Male patients were the most prevalent, 54%. The prevalence of younger patients, less than 31 years old, was 4.2% but 82.1% of them were from Bahia State. Patients with more than 40 years old, were majority (85.5%). The radiological groups were distributed as follows: group I (35.9%), group II (32.9%), group III (17%) and group IV (14.2%). Dysphagia for solid was common in all radiological groups, however dysphagia for liquids, regurgitation and other gastrointestinal symptoms were significant in groups II, III and IV. Conclusion: Compared to previous studies by the same group in 1975, 1994 and 1995, the number of younger patients decreased and the frequency curve is shifting to older ages.