FANUT - Faculdade de Nutrição
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Navegando FANUT - Faculdade de Nutrição por Por Orientador "Botelho, Patrícia Borges"
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Item Efeito do extrato seco de chá verde e da metformina sobre o controle dos fatores de risco para o diabetes mellitus tipo 2 em mulheres com excesso de peso(Universidade Federal de Goiás, 2016-02-26) Ferreira, Monallisa Alves; Mota, João Felipe; http://lattes.cnpq.br/7179509845172692; Stringhini, Maria Luiza Ferreira; http://lattes.cnpq.br/3705544548242014; Botelho, Patrícia Borges; http://lattes.cnpq.br/1410018547168121; Bressan, Josefina; Botelho, Patrícia Borges; Botelho, Patrícia BorgesAim: The aim of this study was to evaluate the effect of dry green tea extract isolated and/or combined with metformin on diabetes type 2 risk factors in women with overweight. Methods: A double-blind, placebo-controlled, randomized trial which 120 obese women were randomly assigned in a double-blind manner to 1 of 4 groups: Control (n = 29; 1g of cellulose); Green tea (n = 32; 1g of dry green tea extract); Metformin (n = 28; 1g of metformin); Green tea + Metformin (n = 31; 1g of dry green tea extract + 1g of metformin). Anthropometric measurements, body composition, fasting blood samples were evaluated. Results: After 12 weeks, green tea had positive effect on glycemic control. In contrast, the metformin led to an increase of HbA1c concentration (0.048 ± 0.189%; p = 0.017). It also reduced body weight (-1.318 ± 0.366, p = 0.034) as well as decreased lean body mass (-1.249 ± 0.310; p = 0.009). Regarding the lipid parameters, green tea significantly reduced total cholesterol and LDL-c. Conclusion: The isolated action of green tea was superior to metformin on glycemic control and lipid profile. Therefore, green tea dry extract may be a better alternative to treat risk factors to DM2 in overweight women than metformin.Item Efeito de um extrato aquoso de folhas e talos de beterraba (beta vulgaris) orgânicos sobre a lipemia pós-prandial e marcadores de distúrbios pressóricos em indivíduos com dislipidemia(Universidade Federal de Goiás, 2016-03-31) Gomes, Anna Paula Oliveira; Mortoza, Andrea Sugai; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4797911P4; Mota, João Felipe; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4710167P0; Botelho, Patrícia Borges; http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4550430T3; Faria, Eliana Cotta de; Cominetti, Cristiane; Botelho, Patrícia BorgesAim: To analyze whether the acute effect of an aqueous extract of beet leaves and stalks containing different concentrations of polyphenols on lipemia and markers of blood pressure disorders in dyslipidemic subjects after a high-fat meal. Methods: In a randomized, double-blind, placebo-controlled crossover design, 13 dyslipidemic subjects were fed a single high-fat meal and supplemented with placebo or aqueous extract of organic beet leaves and stalks (31.96 mg or 77.53 mg of polyphenols) with 1-week wash-out period. Blood samples were obtained at fasting and 30, 60, 120 and 180 min after intervention. Total cholesterol, HDL, triglycerides, glucose, insulin, nitric oxide and blood pressure were assessed. Results: High fat meal increased triglycerides after 120 (P < 0.001) and 180 minutes (P < 0.001) and reduced HDL after 30 minutes. This reduction was attenuated in both groups that received aqueous extract of beet leaves and stalks after 120 minutes (P = 0.005). There were no treatment differences in triglycerides, glucose, insulin and nitric oxide levels in all times. In contrast, it was observed a reduction in diastolic blood pressure from baseline (T0) in both groups that received aqueous extract of beet leaves and stalks. Conclusion: The aqueous extract of beet leaves and stalks containing only 31.96 mg of polyphenols was able to attenuate the reduction of HDL induced by a high fat meal similarly to extract containing a higher polyphenols concentration.Item Efeito da suplementação de creatina associada a um programa de treinamento físico resistido sobre massa magra, força e massa óssea em idosos(Universidade Federal de Goiás, 2015-03-27) Pinto, Camila Lemos; Mota, João Felipe; http://lattes.cnpq.br/7179509845172692; Botelho, Patrícia Borges; http://lattes.cnpq.br/1410018547168121; Gualano, Bruno; Cominetti, Cristiane; Mota, João FelipeThe aim of this study was to examine the efficacy of creatine supplementation associated with resistance training on lean mass, strength and bone mass in the elderly. This was a 12-week, parallel-group, double-blind, randomized, placebocontrolled trial. The individuals were randomly allocated into one of the following groups: placebo plus resistance training (PL + RT) and creatine supplementation plus resistance training (CR + RT). The participants were assessed at baseline and after 12 weeks. The primary outcomes were lean mass and strength, assessed by dual energy X-ray absorptiometry (DXA) and ten-repetition maximal (10RM) tests, respectively. Secondary outcomes included lumbar spine, right and left femoral neck, dual femur and whole body bone mineral density and whole body bone mineral content, assessed by DXA. The CR+RT group had superior gain in lean mass when compared with the PL+RT group (p = 0.02). Changes in 10RM tests in bench press and leg press exercises, body composition, bone mineral density and content of all assessed sites did not significantly differ between the groups (p > 0.05). In conclusion, 12 weeks of creatine supplementation associated with resistance training resulted in increased lean mass.