FO - Faculdade de Odontologia
URI Permanente desta comunidade
Navegar
Navegando FO - Faculdade de Odontologia por Por Orientador "Estrela, Carlos"
Agora exibindo 1 - 12 de 12
Resultados por página
Opções de Ordenação
Item Efeito da terapia fotodinâmica sobre biofilme de Enterococcus faecalis e estrutura dentinária(Universidade Federal de Goiás, 2016-05-05) Alves, Denise Ramos Silveira; Alencar, Ana Helena Gonçalves de; http://lattes.cnpq.br/2039898015468283; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Souza, João Batista de; Decúrcio, Daniel de Almeida; Pécora, Jesus Djalma; Barletta, Fernando BrancoObjective: Evaluate the effect of photodynamic therapy (PDT) on Enterococcus faecalis biofilm in infected root canals and on dentin structure. Methods: Twenty-one root canals of a sample of 24 extracted single-rooted human teeth were infected by E. faecalis for 60 days to form biofilm. The antimicrobial strategies tested were (n=3 in each group): root canal preparation using NiTi rotary instruments, 2.5% NaOCl and 17% EDTA irrigation, and PDT with 0.01% methylene blue (group I) or 0.01% malachite green (group II); root canal preparation using NiTi rotary instruments, 2.5% NaOCl and 17% EDTA irrigation, and PDT with 0.01% methylene blue (group III); PDT with 0.01% methylene blue without root canal preparation (group IV); root canal preparation using NiTi rotary instruments, 22.5% NaOCl and 17% EDTA irrigation, and no PDT (group V); 2.5% NaOCl irrigation with no root canal preparation, and 17% EDTA irrigation (group VI); positive control (group VII). Three roots were not infected and were used as negative controls (group VIII). Samples for microbiological tests were collected using three sterile paper points, later stored in BHI and incubated at 37o C for 48 hours at three time points: before (S1) and after (S2) root canal preparation, and after PDT application (S3). Bacterial growth was analyzed according to turbidity of culture medium, presence of bacteria, and spectrophotometric optical density (nm). Specimens were sectioned and prepared for SEM analysis of dentin structure. Results: Bacteria were found at S1, S2 and S3 in all experimental groups. Optical density of culture media at S2 and S3 in groups I, II and III were lower than at S1, but not statistically different. Optical density of culture media at S2 was 28.70% and 24.67% lower than at S1 in groups I and II; after PDT, optical density was 90.00% (group I) and 37.30% (group II) lower. In group III, it was 97.70% lower at S2 and an additional 92.00% lower after PDT. In group IV, optical density increase 3.2%. Dentin analysis after PDT revealed areas of melting and recrystallization, peritubular dentin projections, intertubular dentin erosion and fusion of dentinal tubule openings, which made dentin surface irregular. Some dentinal tubules were obliterated, and there were changes in the shape of their openings. Conclusion: PDT applied after root canal preparation using manual or rotary files was not effective in eliminating E. faecalis completely. PDT changed dentin structure and resulted in dentin melting and recrystallization, as well as in dentinal tubule erosion and obliteration.Item Expressão de marcadores de células-tronco mesenquimais em abscesso e granuloma periapical(Universidade Federal de Goiás, 2019-05-07) Barbosa, Mateus Gehrke; Silva, Brunno Santos de Freitas; http://lattes.cnpq.br/1575170017237525; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Silva, Julio Almeida; Sousa Neto, Manoel Damião deIntroduction: The relationship between inflammation, the formation of periapical lesions and mesenchymal stem cells need further elucidation. Evidence for the characterization of mesenchymal stem cells in periapical abscesses and granulomas becomes opportune for a better understanding of the periapical lesion microenvironment formation. Objective: To evaluate the immunohistochemical expression of CD44, CD73, CD105 and CD45 markers of mesenchymal stem cells in periapical lesions of teeth with histopathological diagnosis of abscess and periapical granuloma by means of immunohistochemistry. Methodology: Samples of periapical lesions diagnosed as abscess (n = 10) and periapical granuloma (n = 10) were selected from teeth of patients attended at the Emergency Department of the Faculty of Dentistry of the Federal University of Goiás (FO / UFG) kept in blocks of paraffin on the bench of the Endodontic Science laboratory. The diagnostic confirmation of the samples was made from the analysis of the slides with hematoxylin and eosin staining. The immunohistochemical expression of the CD44, CD73 and CD105 positive markers and the CD45 negative marker was analyzed, and the presence or absence of positive cells was evidenced in the area examined. It was considered as immunohistochemical expression of mesenchymal stem cells when there was the expression of the three positive markers and no expression of the negative marker. The frequencies of the qualitative variables were obtained. Qualitative variables were assessed using the Chi-square test. Values of p <0.05 were considered significant. Results: Expression of mesenchymal stem cells was confirmed by positive expression of CD44, CD73 and CD105 markers and absence of CD45 marker expression. This occurred 40% (4/10) in cases of abscesses and in the group of granulomas in 20% (2/10) of the cases. Conclusions: Abscess and periapical granuloma presented immunohistochemical expression of mesenchymal stem cells. The cases of periapical abscesses presented a higher percentage of immunohistochemical expression for mesenchymal stem cells than those of periapical granumola.Item Correlação entre cor da coroa dentária e a saturação de oxigênio em dentes submetidos a procedimentos clareadores(Universidade Federal de Goiás, 2021-03-26) Carvalho, Igor César Ribeiro de; Alencar, Ana Helena Gonçalves de; http://lattes.cnpq.br/2039898015468283; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Barletta, Fernando Branco; Silva, Júlio AlmeidaObjective: To evaluate the correlation between the color of the dental crown and the result of the pulse oximeter in healthy teeth before and after bleaching procedures. Materials and methods: According to the sample calculation, it would be possible with 62 teeth to detect as statistically significant correlation coefficients between the color of the dental crown and the result of the pulse oximeter, with moderate magnitude (r = 0.40) considering a power of 90%. This is a clinical trial with a sample consisting of 70 participants. The color of the dental crown of 70 healthy upper central incisors was assessed using a spectrophotometer and the oxygen saturation level of the pulp was recorded using a pulse oximeter. Both measurements were made before and 30 days after the completion of the bleaching procedures. The bleaching was performed by the combined technique, with the application of the 35% hydrogen peroxide whitening gel, in the office stage, and with 10% carbamide peroxide, in the home stage, for 16 days. The influence of each coordinate on the color difference of the dental crown was analyzed according to ABNT (2004). The symmetry of the variables was verified by the Kolmogorov Smirnov test, and the quantitative variables were described by means and standard deviations. The correlation between quantitative variables was established using Pearson's correlation coefficient. The level of significance considered was 5%. Results: A statistically significant change was observed between values recorded by the pulse oximeter before (85.0% ± 4.1) and after 30 days after the completion of the bleaching procedures (86.4% ± 2.3), as well as between the values of the color coordinates initially detected (L * = 89.0 ± 2.8; a * = -1.7 ± 0.7; b * = 20.7 ± 3.2) and 30 days after the tooth whitening (L * = 91.2 ± 2.6; a * = - 3.0 ± 0.6; b * = 13.5 ± 2.5). 30 days after the completion of the bleaching procedures, the dental crowns were clearer with a difference between L * s equal to 1.4, more greenish with a difference between a * s equal to 1.3, and more bluish, with a difference between b * s equal -7.2. There was no correlation between the values of the coordinates L *, a * and b * and the results recorded by the pulse oximeter in the initial period, r = -0.22, r = 0.02, r = 0.11, respectively, nor after 30 days after the completion of the bleaching procedures, r = -0.20, r = 0.01, and r = -0.12, respectively. Conclusion: Changes in the pulse oximeter records do not correlate with the color change of the dental crown promoted by bleaching procedures.Item Avaliação da distância da junção amelocementária a crista óssea alveolar pré e pós-tratamento ortodôntico(Universidade Federal de Goiás, 2015-03-12) Castro, Luma Oliveira; Alencar, Ana Helena G.; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Alencar, Ana Helena G.; Decurcio, Daniel de Almeida; Guedes, Orlando de AguirreTo evaluate the distance from the cementoenamel junction to pre alveolar crest pre and post-orthodontic treatment through Cone Beam Computed Tomography (CBCT). Methodology: We selected from a database of previous dental CBCT image data and subsequent orthodontic treatment of 30 patients who were diagnosed with malocclusion Angle Class I and mild to moderate crowding. The distance between the cementoenamel junction to bone crest of the buccal (n = 720) and palatal or lingual (n = 720) was measured in 24 teeth for each patient using a software tool specific Xoran version 3.1.62 (Xoran Technologies, Ann Arbor, MI, USA). Statistical analysis of pre and post-orthodontic treatment was assessed using the Wilcoxon test and significance level of p <0.05. Results: It was observed that at least one tooth of each patient had a face with increasing distance from the alveolar crest to orthodontic post-treatment cementoenamel junction. This increase was observed in 822 (57%) of the 1440 evaluated root faces. The buccal surface of lower central incisor showed the highest frequency of increasing distance (75%) and the palatal surface of maxillary lateral incisor presented the smallest (40%). It was found that the 1440 root faces previously assessed orthodontic treatment, 162 (11%) had distance from the cementoenamel junction to bone crest greater than 2 mm (alveolar bone dehiscence), and orthodontic aftertreatment faces evaluated, 279 (19 %). Conclusion: It can be concluded that there was a change of the distance from the junction amelocemetária alveolar crest orthodontic post-treatment; and distance greater than 2mm orthodontic pretreatment orthodontic 11% and 19% after treatment.Item Análise da hibridização dentinária na alteração cromática coronária frente ao uso de cimentos obturadores do canal radicular e cimento portland(Universidade Federal de Goiás, 2021-02-22) Chaves, Lucas Silva; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Decurcio, Daniel de Almeida; Guedes, Orlando AguirreObjective: This study evaluated the influence of dentin hybridization in the coronary chromatic alteration of bovine teeth when using different endodontic cements based on calcium silicate and Portland cement. Material and method: 200 bovine central incisors were divided into two groups: G1 with the presence of dentin hybridization and G2 without the presence of dentin hybridization. The teeth were subjected to colorimetric analysis using the Easyshade spectrophotometer at four different times: determining the color of the dental substrate before root canal filling; seven days after root canal filling, sixty days after root canal filling and one hundred eighty days after root canal filling. The data were tabulated and evaluated for normality and homogeneity by the Shapiro-Wilk and Levene tests, respectively. Two-way analysis of variance was performed, with Sidak's post-test for multiple comparisons, with a significance level of 5% (α = 0.05). Results: Dentin hybridization influenced the coronary chromatic alteration of Sealapex cement after 7 days and in Bio-C Sealer and AH Plus cements after 60 days, but all endodontic cements caused clinically noticeable chromatic changes after 7 days, 60 days and 180 days, independent of hybridization. After 7 days, the AH Plus endodontic cement obtained the highest ΔE * when hybridized and the Endofill endodontic cement obtained the highest ΔE * when not hybridized. After 60 days, the AH Plus endodontic cement obtained the highest ΔE * when hybridized and non-hybridized. After 180 days, Sealapex endodontic cement obtained the highest ΔE * when hybridized and AH Plus endodontic cement obtained the highest ΔE * when not hybridized. Conclusion: All endodontic cements caused clinically perceptible chromatic changes in the endodontically treated teeth after 7 days, 60 days and 180 days, regardless of dentin hybridization. The studied endodontic cements behaved in different ways regarding a coronary chromatic alteration, being difficult to predict a unique behavior.Item Prevalência de dentes pilares de prótese fixa em subpopulação adulta brasileira(Universidade Federal de Goiás, 2012-03-09) Crosara, Mariana Borges; Souza, João Batista de; http://lattes.cnpq.br/0642108682158061; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Alencar, Ana Helena Gonçalves de; Rocha, Sicknan Soares da; Barletta, Fernando BrancoObjective: The purpose of this cross-sectional study was to evaluate the prevalence of pillar teeth for fixed prostheses in a subpopulation of adult Brazilians. Methods: Panoramic radiographs of a total of 1401 patients, performed between August 2002 and September 2007, were randomly selected from the database of the Radiological Center of Orofacial Images of Cuiabá (CROIF, Cuiabá, MT, Brasil). A total of 1401 radiographs were examined to determine the frequency of pillar teeth for fixed prostheses. The data were collected and tabulated, regarding age, gender and dental group. The statistical treatment analyzed the data about the frequency distribution and chi-square test. The significance level was set at α = 5%. Results: We evaluated 29,467 teeth, and of these, 4,967 (16.8%) were pillars of fixed prosthesis. High prevalence of pillar teeth for fixed prosthesis was observed in female subjects (61.2%) and aged between 46-60 years (49.9%). Upper and lower premolars were the teeth more often involved in rehabilitation, 20.5% and 17.2%, respectively. Dental absences were identified in 24.8% of the sample. Conclusion: The prevalence of pillar teeth associated with fixed prosthesis was 16.8%, being more frequent in upper incisors and premolars of female subjects.Item Efeito antibacteriano de extrato de própolis vermelha e verde em canais radiculares infectados por enterococcus faecalis(Universidade Federal de Goiás, 2015-03-20) Endo, Mônica Misae; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Decurcio, Daniel Almeida; Guedes, Orlando AguirreThe objective of this study was to investigate the antibacterial effect of alcoholic extracts of 30% red propolis, 40% green propolis and 2.5% sodium hypochlorite in different irrigation protocols in root canals infected Enterococcus faecalis. Twenty-four extracted teeth with one root canal were selected, the prepared root canals and inoculated with E. faecalis for 60 days. The teeth were randomly divided into eight experimental groups (n = 3) and 2 control groups (n = 3). In all experimental groups were performed root canal preparation and two irrigation protocols - passive ultrasonic irrigation and conventional irrigation. In the groups 1, 3, 5 and 7 was made ready root canal associated with conventional irrigation to 30% propolis, 40% propolis, 2.5% sodium hypochlorite and distilled water, respectively. In groups 2, 4, 6 and 8 was performed root canal preparation associated with passive ultrasonic irrigation and irrigated with the same solutions described above. In the groups 9 and 10 were the controls - negative (root canals uncontaminated) and positive (root canals contaminated untreated). Samples of root canals were collected and immersed in 7 mL of BHI for 48 hours, incubated at 37 °C. The bacterial growth was assessed by turbidity of the culture medium. The results showed antibacterial effectiveness of the alcoholic extract of 30% red propolis and 2.5% sodium hypochlorite when used conventional irrigation and passive irrigation, only after 20 minutes. The irrigation protocols and the substances tested were not effective to eliminate bacterial dentin contamination with E. faecalis.Item Efeito de diferentes momentos do selamento dentinário na resistência de união à dentina exposta à substâncias químicas auxiliares a endodontia(Universidade Federal de Goiás, 2020-03-03) Izelli, Thabata Frederico; Carvalho, Marco Aurélio de; http://lattes.cnpq.br/0482978464903802; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Decurcio, Daniel de Almeida; Lazari, Priscilla Cardoso; Estrela, CarlosChemical substances used in endodontic treatment can affect the quality of adhesion in the final restoration. The moment of dentin hybridization (HD) can act to minimize the effects of these substances on dentin and influence the quality of adhesion. This study evaluated the timing of HD and different chemical substances in dentin bond strength in human teeth. Twenty human molars were distributed in four experimental groups: G1. RD - direct restoration in composite resin, the control group being without exposure to chemical substances or temporary restoration; G2. HDT - late dentin hybridization with HD at the time of final restoration, after exposure to chemicals and temporary restoration; G3. HDI - immediate dentin hybridization with HD after simulation of endodontic treatment and prior to provisional restoration; G4. HDP - previous dentin hybridization with HD prior to exposure to chemical substances and temporary restoration. The coronary dentin was exposed, submerged with 2.5% sodium hypochlorite, 17% EDTA and endodontic cement, molded with addition silicone, temporarily restored, and stored for 2 weeks in artificial saliva. Then it was restored with composite resin and the microtensile test was performed after 24 hours. The toothpicks were cut to a size of 1mm² and subjected to microtraction at 0.05mm / min (MPa) in the universal testing machine. After assessing normality and homogeneity, the microtensile bond strength values were analyzed using ANOVA, a 5% significance test, followed by a post hoc test (Tukey). The highest bond strength value was found in the control group (42.39 MPa ± 5.69), followed by the HDP group (41.51 MPa ± 3.68), the HDI group (21.16 MPa ± 9.66) and the lowest value in the HDT group (9.86 MPa ± 1.30). The control group (RD) showed no statistically significant difference in relation to the previous dentin hybridization (HDP) approach. The HDI and HDT groups showed a decrease in the tensile strength value when compared to the control group of 76.7% and 50.1%, respectively. It can be concluded that dentin hybridization prior to exposure to chemical substances used in endodontic treatment positively influenced the microtensile bond strength of the studied samples.Item Avaliação de cimentos e técnicas de obturação no preenchimento de istmos radiculares usando um novo software de tomografia computadorizada de feixe cônico(Universidade Federal de Goiás, 2022-05-25) Morais, André Luiz Gomide de; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Oliveira, Helder Fernandes de; Siqueira, Patrícia Correia de; Silva, Júlio Almeida; Silva, Brunno Santos de Freitas; Estrela, CarlosAim: To evaluate the sealing ability of root isthmuses using different sealers and root canal filling techniques using a new Cone Beam Computed Tomography software (e-Vol DX). Methodology: 120 lower molars extracted from patients with indication for extraction were used. The teeth were divided into 6 groups according to the endodontic sealer and filling technique: G1: AH Plus® + lateral condensation technique (n=20), G2: AH Plus® + Tagger's hybrid technique (n=20), G3: AH Plus® + single cone technique (n=20), G4: BioRoot RCS + lateral condensation technique (n=20), G5: BioRoot RCS® + Tagger hybrid technique (n=20) and G7: BioRoot RCS® + single cone technique (n=20). The teeth were instrumented using the Wave One Gold® reciprocating system, irrigation performed with 2.5% sodium hypochlorite and EDTA (using ultrasonic passive irrigation) and then all canals were filled according to the division of the groups. Sealing evaluation was performed using scores. Nonparametric statistics were used for its analysis and the description was performed by median, minimum and maximum. Mann Whitney test was used to compare the scores between the sealers and Kruskal-Wallis test followed by Dunn-Bonferroni post hoc tests between the obturation techniques and groups. To compare scores obtained with and without Blooming Artifact Reduction (BAR) filter of e-Vol DX software, Wilcoxon test was used. Results: Results showed there was a significant difference in sealing lower molar isthmus using endodontic sealers studied in apical third with BAR (p=0.016), with scores being higher for AH Plus®. There were differences in sealing of lower molar isthmus using different filling techniques in middle and apical thirds. For middle third without BAR, difference was between single cone and Tagger's hybrid techniques (p=0.011) as well as for apical third without BAR (p<0.001). For middle third with BAR, difference was between single cone technique and lateral condensation (p=0.043) and Tagger hybrid (p=0.009) techniques. For apical third with BAR, the difference was between Tagger's hybrid technique and single cone (p<0.001) and lateral condensation (p=0.041) techniques. When comparing the sealing scores using different filling techniques and types of sealer, there were differences between G2 and G3 (p=0.015) and G2 and G6 (p=0.024) in apical third without BAR. Using BAR tool, statistical differences were as follows: in cervical third between G2 and G6 (p=0.023); in middle third, between G2 and G6 (p=0.072); in apical third, G6 had lower scores than G1 (p=0.046), G2 (p=0.002) and G5 (p=0.011) and G4 had lower scores than G2 (p=0.023). When comparing isthmus sealing scores with and without using BAR tool, there were significant differences, with higher values without using the tool, in all thirds. It is concluded that, when evaluating sealing ability of root isthmus using different sealers and filling techniques with e-Vol DX software, the best combination was the use of AH Plus and Tagger's hybrid technique. Using BAR filter of the eVol DX software in CBCT images showed more empty spaces in filling mass due to the reduction of white expansion, making tomographic image more reliable.Item Utilização de estratégia dinâmica de navegação em imagens axiais de tomografia computadorizada de feixe cônico na detecção da frequência de istmo radicular na dentição permanente humana(Universidade Federal de Goiás, 2015-03-13) Rabelo, Luiz Eduardo Gregoris; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Pécora, Jesus Djaalma; Souza, João Batista; Alencar, Ana Helena deThis study determined the frequency of root isthmuses (RI) in human permanent teeth using map-reading dynamics and cone beam computed tomography (CBCT) images. A sample of 1,400 teeth was selected from CBCT scans of 618 patients (394 women; 43.4 mean age-years). RI were detected longitudinally using map-reading dynamics on axial images by CBCT using slices with a 0,1 mm thick, from the pulp orifice to the root apex, and findings were recorded into seven categories: 1. beginning and end in cervical third; 2. beginning in cervical third and end in middle third; 3. beginning in cervical third and end in apical third; 4. beginning and end in middle third; 5. begin in middle third and end in apical third; 6. beginning and end in apical third; 7. no isthmus. The categorical variables, described as frequencies (%), were analyzed using a chi-square test (2) with Yates correction or the Fisher's exact test. Quantitative variables were compared using the Student t test for independent samples. RI is an anatomic structure of common occurrence in human permanent teeth, except in maxillary anterior teeth. The higher frequencies of root isthmus (87.9%) in human permanent teeth were found in mandibular first molars. The frequency of RI according to gender was not significantly different (p>0.05), except in mandibular central incisors. RI was less frequent among older patients. The higher frequency of four root canals (76%) and four apical foramina (33%) was found in maxillary first molars.Item Microanálise de superfície e caracterização química de cimentos endodônticos(Universidade Federal de Goiás, 2013-01-15) Sampaio, Felipe Cavalcanti; Alencar, Ana Helena Gonçalves de; http://lattes.cnpq.br/2039898015468283; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Alencar, Ana Helena Gonçalves de; Veloso, Heloísa Helena Pinho; Guedes, Orlando AguirrePurpose: to assess the surface and evaluate the chemical composition of root canal filling materials by scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). Methods: eighteen polyethylene standard tubes were filled with the tested materials: Sealapex®, Sealer 26®, MTA Fillapex®, Pulp Canal Sealer®, Endofill® and AH Plus®. After 48 hours at 37°C and 95% relative humidity, the samples were surface-sputtered with gold, led to SEM and the images analyzed at 5,000X magnification. Then, the elements distribution and chemical composition were determined by EDX. The results were evaluated qualitatively (SEM images and elements distribution maps) and quantitatively (weight percentage). Results: the surface analysis revealed that the sealers presented different regularities, with an uniform distribution of elements, with particles of similar sizes and variable shapes in EDX microanalysis. Calcium oxide and hydroxide based sealers (Sealapex® and Sealer 26®) presented calcium peaks of 53.58wt.% and 65.00wt.%, respectively. MTA Fillapex® presented 30.58wt.% of calcium and high amounts of silicon (31.02 weight%) and bismuth (27.38 weight%). Zinc oxide and eugenol based sealers, Pulp Canal Sealer® and Endofill®, showed zinc quantities of 67.74wt% and 63.16wt.%, respectively. AH Plus® had higher amount of zirconium (64.24wt.%). The materials presented elements incompatible with the composition described by the manufacturer. Conclusions: the root canal sealers’ surfaces showed different. The elements presented uniform distribution, with particles of similar sizes and variable shapes. Chemical elements were found in the root canal sealers not described by the manufacturers.Item Expressão imuno-histoquímica de células - tronco mesenquimais em lesões periapicais crônicas(Universidade Federal de Goiás, 2019-03-07) Souza, Paulo Otávio Carmo; Silva, Brunno Santos de Freitas; http://lattes.cnpq.br/1575170017237525; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Decurcio, Daniel de Almeida; Sousa Neto, Manoel Damiao deIntroduction: Mechanisms of the pathogenesis process of chronic periapical lesions still require further discussion. Mesenchymal stem cells (MTC) present in the periapical region may participate in the process of genesis and development of chronic apical periodontitis, due to the ability of migration and differentiation in inflammatory environments. Objective: To evaluate the immunohistochemical expression of CTM markers (CD44, CD45, CD73 and CD105) in chronic periapical lesions. Method: Ten samples of periapical cysts and ten periapical granulomas were selected from the block file of the endodontic science laboratory of the Faculty of Dentistry of the Federal University of Goiás to perform an immunohistochemical reaction. The frequency of the presence or absence of the CD44, CD45, CD73 and CD105 markers was assessed under light microscopy in the fields of higher expression, and the immunohistochemical expression of CTM was determined when there was positive co-expression on the CD44, CD73 and CD105 markers and negative expression for the CD45 marker. The frequency of the qualitative variables were obtained and evaluated by the Chi-square test. Values of p <0.05 were considered significant. Results: In the periapical granulomas, 20% (2/10) presented co-expression for CTM positive markers (CD44, CD73 and CD105) associated with no expression for the CTM (CD45) negative marker. In the periapical cysts group there were no cases (0/10) of immunohistochemical coexpression for CD44, CD73 and CD105 markers associated with absence of CD45 expression. Conclusion: In the periapical cysts there was no immunohistochemical expression of CTM and the immunohistochemical expression occurred in 2 of the 10 cases of periapical granulomas.