Navegando por Assunto "metabolismo"
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Item Análise bioquímica e equilíbrio ácido-base em Biomphalaria glabrata (Say, 1818), hospedeiro intermediário do Schistosoma mansoni (Sambon, 1907), sob a exposição ao Stryphnodendron polyphyllum (Martius, 1837), planta moluscicida do Cerrado brasileiro.(Universidade Federal de Goiás, 2006-03-31) FERREIRA, Cirlane Silva; BEZERRA, José Clecildo Barreto; http://lattes.cnpq.br/9491755585617846The state of Goiás represents a high risk to schistosomiasis stablishment area The presence of the intermediate host Biomphalaria sp added to high migration levels of people from endemic regions of the country are evidences that favour the installation of this disease life cycle In this state of Goiás there are reports of high parasitary intensity and even cases of paraplegia associated with schistosomiasis. The Stryphnodendron polyphyllum (Martius 1837) known locally as Barbatimão de folha pequena is reported as a molluscicide plant This paper assesses the activity of gross bark extracts from S polyphyllum on the metabolism and on the acid-alkaline balance of B glabrata The mollusks were exposed to the extract at 25 and 50 mg/L concentrations for 24 hours and compared to a control group The concentrations of glucose calcium urea proteins and the activity of the following enzymes dehydrogenases lactate and aminotransferases were estimated using the spectrophotometry method The organic acids citrate propionate α- cetoglutarate succinate acetate malate fumarate pyruvate and lactate were detected and quantified using the liquid chromatography method Of all the organic acids found in the hemolymph, only citrate and propionate presented a significant alteration The acid-alkaline balance was verified by measuring the concentrations found in the pH oxygen carbonic gas carbonate ions and oxygen saturation using Radiomiter equipment The S polyphyllum extract tested proved effective due to celular toxicity on B glabrata(Say 1818) Alterations verified in the biochemical dosages reflect the metabolic disturbances in the hemolymph of the mollusk The Cirlane Silva Ferreira x extract interference caused an increase in the levels of glucose urea calcium aspartate alanine aminotransferases and carbonic gas pressure simultaneously causing a decrease in the levels of lactate dehydrogenase pH oxygen pressure carbonate ions and oxygen saturation This study confirms the bioactivity of the S polyphyllum aqueous extract on B glabrata One of the main contributions of the methodology used is that it enabled observation after direct contact with the extract that proved bioactivity on the metabolism of the mollusk The analysis of the aqueous extract taken from the bark of the barbatimão may be the basis for new and less toxic as well as less costly alternative for the control of schistosomiasis in Brazil, where the savannah is vast and financial resources are often scarce in the health sectorItem Conformação corporal e bioquímica sanguínea de cadelas adultas castradas alimentadas ad libitium(Universidade Federal de Goiás, 2009-12-15) GUIMARÃES, Patrícia Lorena da Silva Neves; STRINGHINI, José Henrique; http://lattes.cnpq.br/8505634095383289; BORGES, Naída Cristina; http://lattes.cnpq.br/9181279951885005; FIORAVANTI, Maria Clorinda Soares; http://lattes.cnpq.br/8772502020076257The obesity is a physical condition more frequent in each time in the population of pets, being able to contribute for the sprouting of systemic alterations capable to compromise the health of the animals. Ahead of the displayed one, this experiment was developed in the Veterinarian Hospital of the Federal University of Goiás, with 26 adult female dogs, castrated and without defined brand, they had been fed with commercial diet ad libitum, during 36 weeks, and had biweekly accompaniment of the nutritional state by means of clinical parameters (body condition score - BCS), morphometrics (abdominal perimeter, thoracic perimeter, thigh perimeter) and for the equations for determination of the percentage of corporal fat and index of corporal mass (IMC1=weightkg/height of withersm; IMC2=weightkg/hight of withers2 m; IMC3=weightkg/spine lengthm; IMC4=weightkg/spine length2 m). The metabolic accompaniment was carried through, monthly, by means of evaluation of the serum biochemistry (glucose, urea, creatinin, albumin, triglycerides, total cholesterol and HDL). The objective of the work was to verify the associations between the morphometrics variables and the serum biochemistries, by means of the multivariate analysis of main components. In the results, bigger association between corporal weight was perceived, thoracic perimeter and of thigh. Moreover, associations between the IMC3 and IMC4 were verified, respectively, by abdominal perimeter and BCS. The percentage of corporal fat was antagonistic to the perimeter of the thigh and corporeal weight and was associated to BCS and IMC4. Related to the serum biochemistry, associations between glucose and creatinin had been observed; and between the total cholesterol and HDL. Antagonism of the albumin with triglycerides, total cholesterol and HDL was verified. Moreover, the percentage of weight gain and the urea texts had been inversely proportional to the concentrations of glucose and creatinin. The present study allowed to conclude that the morphometric, especially the measure of thoracic perimeter and the classification of body condition score constitute efficient methods of monitorament of the corporal conformation, and also, to conclude that, dogs submitted to the weight gain for a short period of time, had been capable to develop compensatory mechanisms of keeping the homeostasis of metabolism, keeping the biochemical concentrations inside of the values of reference.Item FARINHAS DE RESÍDUOS DE ABATEDOUROS AVÍCOLAS EM DIFERENTES GRAUS DE PROCESSAMENTO EM RAÇÕES PRÉ-INICIAIS E INICIAIS DE FRANGOS DE CORTE(Universidade Federal de Goiás, 2008-08-28) LABOISSIERE, Michele; CAFÉ, Marcos Barcellos; http://lattes.cnpq.br/9860968235125158; LEANDRO, Nadja Susana Mogyca; http://lattes.cnpq.br/3136809931691012; STRINGHINI, José Henrique; http://lattes.cnpq.br/8505634095383289In this experiment, the inclusion of viscera and bone meal (FVO) and feather and blood meal (FPS) according to its processing grade was evaluated in broiler pre-starter and starter rations. The experiments were conducted in the poultry experimental facilities of the Veterinary College of the Federal University of Goiás (EV/UFG), located in Goiânia, Brazil. A total of four experiments were carried out to evaluate performance, digestibility and intestinal biometry of broilers fed diets containing viscera and bone meal (FVO) with different moisture levels in processing and feather and blood meal (FPS) with different pressing levels in processing in pre-starter (one to seven days of age) and starter (eight to 21 days of age). In the first experiment, 9% inclusion of FVO with different moisture levels at processing (4, 5 and 6%) in pre-starter rations. In the second experiment, the same moisture levels of FVO were analyzed for starter rations. In the third experiment, 9% inclusion of FPS with different hydrolysis pressing at processing (2,0, 2,5 e 3,0 kg/cm2) in pre-starter ration was tested. In the experiment 4, the same hydrolysis pressing levels were tested for FPS but now at starter rations. The experiment was conducted in a randomized block design, and the criteria to the blocks determination was the battery-cage, with four treatments and five replications of 12 birds each, in a total of 20 experimental units. The statistical analysis was done using UFV/SAEG (2000) and means compared as Tukey test (%5). Variables tested were: live weight, weight gain, feed intake, feed-to-gain ratio, dry matter, nitrogen and ether extract digestibility, dry matter, nitrogen and ether extract retention and biometric indexes of digestive organs. The results indicated that 9% of FVO or FPS didn t affect the performance results. To prestarter phases, the best results were obtained with diets processed with FVO with 5% moisture and FPS with 2,5 kg/cm2 of hydrolysis processing. For starter rations, FVO or FPS didn t affect broiler performance. The poultry by-products processed for animal feeding can be used without performance lost but is important to know the nutritional processing of these ingredients.Item Ação leishmanicida de extratos de plantas no desenvolvimento de promastigotas de Leishmania amazonensis e estudo do perfil metabólico utilizando a técnica de cromatografia líquida de alta eficiência (CLAE).(Universidade Federal de Goiás, 2006-03-31) MENDES, Josireny Mariano; BEZERRA, José Clecildo Barreto; http://lattes.cnpq.br/9491755585617846Two million new cases of Leishmaniose occur annually in the tropical and subtropical areas of the globe, with a estimate of twelve million people currently infected in world and three hundred and fifty million under infection risk. The Leishmania sort, responsible for the disease, understands many diverse and complex species that present resistance to the drugs used in its treatment, beyond the characteristics undesirable. The effectiveness of the control and treatment of a parasitic disease depends on the detailed knowledge of the cycle of life, metabolism and biology in general of the parasite. The World Health Organization, associated with other agencies of research has stimulated the extract inquiry new of native plants as alternative for the treatment and combat of the parasitic disease In this work one standardized techniques of studies biochemists through liquid chromatography high performace (HPLC) evaluating organic acid excretion and consumption of in promastigotes of Leishmania amazonensis and became fullfilled biotests with Magonia pubescens (tingui) and Glycyrrhisa glabra (alcaçuz) in the concentrations of 25 50 and 100 mg.L-1 The acid had been detected following: lactate oxalate citrate -Ketoglutarate succinate fumarate malate and propionate demonstrated activities in the glycolytic pathway cycle of Krebs and respiratory chain Both the tested extracts had presented leishmanicid action with better effect for Glycyrrisa glabra 100 mg.L-1 and Magonia pubescens 25 mg.L-1 The Glycyrrisa glabra had better action in the stationary phase of growth to opposes it of Magonia pubescens that better acted in the logaritmic phase Chemical components of plants can act directly or indirectly in the metabolism of the parasite affecting essential metabolic pathways