Reanimação volêmica com solução de cloreto de sódio 0,9% em cadelas com suspeita de piometra e sepse

Abstract

Fluid therapy is one of the main goals in the treatment of the septic patient, however, particularities of fluid therapy like volume, rate and which solution to use are a challenge due to the pathophysiological changes of sepsis. The objective of this study was to carry out a bibliographic survey about fluid therapy in sepsis in dogs and evaluate clinically and laboratory the volume resuscitation with sodium chloride solution 0,9% in female dogs with pyometra and suspected sepsis. Were included nine female dogs classified by the criteria of systemic inflammatory response syndrome (SIRS) associated with the specific evaluation of organic failure (SOFA) or hyperlactatemia, attended at the Veterinary Hospital of the Veterinary and Zootechnics School of Federal University of Goiás. After diagnosis, the female dogs received a bolus of 15 ml/kg of 0,9% NaCl over 30 minutes, followed by a maintenance rate of 2 ml/kg/h for seven hours. Clinical parameters were evaluated at baseline, after 30 minutes of bolus and every hour, until completing six hours of evaluation. The laboratory tests were performed at the time of diagnosis and after seven hours of fluid therapy. The main clinical findings were reduction in tachycardia, rectal temperature, and dehydration. In the laboratory, there was a reduction in the lactate value, an increase in plasma chlorine and a reduction in red blood cells, hematocrit, hemoglobin and leukocytes. It was concluded that the use of 0.9% NaCl solution reduced the frequency of tachycardia and lactate concentration in animals with pyometra and suspected sepsis, but increased the incidence of hyperchloremia, without promoting metabolic acidosis.