Desenvolvimento de método químico analítico forense para análise de merla por Análise Térmica e Cromatografia Gasosa de Alta Resolução
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Data
2011-03-18
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Universidade Federal de Goiás
Resumo
An analytical chemical method for the forensic analysis of an illicit drug merla, whose the main constituent is the cocaine was development. Thermogravimetric analysis admitted to understand the thermal behavior of samples and quantifying the stages of mass loss, which together with the quantification endothermic event in DSC, the results were essential for the generation of analytical answers used to construct the data matrix of the statistical analysis. An efficient process for the precipitation of inorganic substances was established, which simultaneously allowed the extraction of two liquid fractions, organic and aqueous, being determinate a partition coefficient of 96,22 % for cocaine, using ethyl acetate as solvent, which showed lower elution time (0.58 min.) among the solvents evaluated. A method by Fast GC for cocaine analysis was developed, reducing the analysis time of 14.5 to 4.5 min was developed, which allowed analyze merla sample and the normalization of the chromatographic peaks of cocaine, demonstrated the great variation of its concentration in merla. Noticed of the potential of the method involving the thermo-analytical and chromatographys techniques to generate experimental results obtained statistically enabled a classification and grouping of samples by Euclidean Distance by the Hierarchical Cluster Analysis (HCA), estimated whether seized samples with different users were manipulated in the same laboratory and if determined city has separate laboratories for illegal preparatiom of drug narcotic.
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cocaína , merla , Fast GC , Análise Térmica , HCA , Química Forense , cocaine , merla , Fast GC , thermal analysis and chromatographic , HCA , Forensic Chemistry
Citação
MEDEIROS, Rodrigo Irani. Development of forensic analytical chemistry method for
examination of merla by Thermal Analysis and High Resolution Gas chromatography. 2011. 114 f. Tese (Doutorado em Ciencias Exatas e da Terra) - Universidade Federal de Goiás, Goiânia, 2011.