Electron paramagnetic resonance (EPR) spectral components of spin-labeled lipids in saturated phospholipid bilayers. Effect of cholesterol
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Data
2013
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Resumo
Electron paramagnetic resonance (EPR) spectroscopy was used to study the main structural accommodations of spin labels in bilayers
of saturated phosphatidylcholines with acyl chain lengths ranging from 16 to 22 carbon atoms. EPR spectra allowed the identification
of two distinct spectral components in thermodynamic equilibrium at temperatures below and above the main phase transition. An
accurate analysis of EPR spectra, using two fitting programs, enabled determination of the thermodynamic profile for these major
probe accommodations. Focusing the analysis on two-component EPR spectra of a spin-labeled lipid, the influence of 40 mol %
cholesterol in DPPC was studied.
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Palavras-chave
EPR, Spin label, Lipid dynamics
Citação
CAMARGOS, Heverton Silva; ALONSO, Antonio. Electron paramagnetic resonance (EPR) spectral components of spin-labeled lipids in saturated phospholipid bilayers. Effect of cholesterol. Química Nova, São Paulo, v. 36, n. 6, p. 815-821, 2013.