Synthesis of 3-Bromotetronamides via amination of 3,4-Dibromofuran-2(5H)-one

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2011

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Resumo

This work describes the direct synthesis of 3-bromotetronamides in good yields through the reaction of 3,4-dibromofuran-2(5H)-one, obtained from furfural, with primary and secondary amines. Aromatic amines were more tolerated than aliphatic and heteroaromatic ones. The X-ray structures of five derivatives are described.

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Enaminones, Tetronamides, Butenolides

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CUNHA, Silvio; OLIVEIRA, Caio C.; SABINO, José R. Synthesis of 3-Bromotetronamides via amination of 3,4-Dibromofuran-2(5H)-one. Journal of the Brazilian Chemical Society, Campinas, v. 22, n. 3, p. 598-603, 2011.