Avaliação clínica toxicólogica preliminar do viticromin® em pacientes com vitiligo
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Data
2005-06
Título da Revista
ISSN da Revista
Título de Volume
Editor
Marize Campos Valadares
Resumo
The Brosimum gaudichaudii Trécul (Moraceae) is a very common herb in brazilian
vegetation called “Cerrado”. This plant is used in the ethnopharmacology for the treatment of the vitiligo.
In this plant are founded the furancoumarins, mainly psoralen and bergapten which have a
photosensibility property responsible for the dermal repigmentation effect. The Brosimum gaudichaudii is
a main active component of a medicine called as Viticromin®, which is made from the inferior part of the
stem and the roots of the plant. Considering the low toxicity of the Brosimum gaudichaudii’s roots extract
in the pre-clinical toxicological studies, in this study we investigated same parameters of the clinical
toxicology of the Viticromin® in vitiligo’s patients on therapy with this drug. The results showed that this
drug produced no significant alteration on the aspects investigated in patients under the drug regimen
studied.
Descrição
Palavras-chave
Brosimum gaudichaudii, Mamacadela, Toxicidade, Toxicity
Citação
LEÃO, Anatel Rocha; CUNHA, Luiz Carlos da; PARENTE, Leila Maria Leal; CASTRO, Lia Cândida Miranda de; CHAUL, Aiçar; CARVALHO, Helena Eterna de; RODRIGUES, Vânia B.; BASTOS, Marciley Alves. Avaliação clínica toxicólogica preliminar do viticromin® em pacientes com vitiligo. Revista Eletrônica de Farmácia, Goiânia, v. 2, n. 1, p. 15-23, jan./jun. 2005. Disponível em: <https://www.revistas.ufg.br/REF/article/view/1943/1876>.