Ultrassonografia da articulação femorotibiopatelar em ovinos submetidos à indução de sinovite por lipopolissacarídeos
Carregando...
Data
2022-03-25
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Goiás
Resumo
Synovitis can be induced in animals through the application of bacterial wall lipopolysaccharide, and shows signs similar to
naturally caused synovitis. Several studies have been carried out using the sheep species as an experimental model to understand
osteoarticular diseases of the femorotibiopatellar joint in humans. There are echographic studies regarding the standardization of
the femorotibiopatellar joint normality in sheep. However, for alterations such as acute synovitis, there is a gap in the literature. The
objective was to serially describe the ultrasonographic aspects of the synovitis process induced by intra-articular infiltration of
lipopolysaccharide from Escherichia coli (E. coli) in the femorotibiopatellar joint in sheep. Twelve healthy crossbred sheep (Santa
Inês x Dorper) were used. Synovitis induction was performed only in the right FTP joints, which were evaluated by serial ultrasound
examination at baseline (M0) and at 12 (M12), 24 (M24), 48 (M48), 72 (M72) and 120 (M120) hours after infiltration with
lipopolysaccharide for the induction of synovitis. The intra-articular application of lipopolysaccharide from E. coli resulted in one
or more sonographic signs of synovitis (increased volume of synovial fluid, pleating of the synovial membrane and cellularity in
the joint cavity), which were identified early, 12 hours after inoculation, and regressed along the evaluated times (p=0.0001), until
disappearing after 120 hours of inoculation.
Descrição
Palavras-chave
Artrite, Claudicação, Joelho, Ultrassom, Sinovite, Arthritis, Lameness, Ultrasound, Stifle joint, Synovitis.
Citação
SILVA, Wanessa Patrícia Rodrigues da; FRANCO, Leandro Guimarães; SILVA, Marco Augusto Machado. Ultrassonografia da articulação femorotibiopatelar em ovinos submetidos à indução de sinovite por lipopolissacarídeos. Ciência Animal Brasileira, Goiânia, v. 23, n. 1, e70607P, 2022. Disponível em: https://www.revistas.ufg.br/vet/article/view/70607.